Identification of metabolites from edible mushroom and their biological evaluation.

To identify bioactive metabolites from the fruiting body of , fourteen metabolites (-) including one undescribed morchesexten A () were isolated. Their structures including absolute configurations were assigned on the basis of spectroscopic data and quantum chemical computational methods. Furthermore, the anti-inflammatory and antioxidant activities of the isolated compounds were evaluated.

Construction of Exosomes that Overexpress CD47 and Evaluation of Their Immune Escape.

Our general purpose was to provide a theoretical and practical foundation for the use of exosomes (EXOs) that have high levels of CD47 as stable and efficient drug carriers. Thus, we prepared EXOs from adipose tissue-derived mesenchymal stromal cells (ADMSCs) that had high levels of CD47 (EXOs) and control EXOs (without CD47), and then compared their immune escape and their resistance to phagocytosis . Nanoflow cytometry was used to determine the CD47 level in these EXOs, and the amount of EXOs that remained in rat plasma at 3 h after intraperitoneal injection.

Glycoside constituents with various antioxidant effects from fresh .

Rupr. (CSR), an edible and medicinal material, is widely cultivated in desert regions of Eastern and Western Asia, Europe, and North Africa. Ten glycoside constituents - including one new songaricumone A () were isolated from the fresh .

Involvement of chemosensory proteins in host plant searching in the bird cherry-oat aphid.

Chemosensory systems are considered to play an important role in host plant selection in herbivorous insects. However, few studies have focused on chemosensory proteins (CSPs) for aphid host-location mechanisms. The roles of CSPs in searching for different Poaceae species (wheat, barley, triticale, maize and sorghum) were tested in Rhopalosiphum padi, an important cereal pest.

Functional Characterization of Two Carboxylesterase Genes Involved in Pyrethroid Detoxification in .

Insect carboxylesterases are major enzymes involved in metabolism of xenobiotics including insecticides. Two carboxylesterase genes, and , were cloned from the destructive agricultural pest . Quantitative real-time polymerase chain reaction showed that and were predominantly expressed in fat body and midgut, respectively; developmental expression analyses found that the expression levels of both CarEs were significantly higher in fifth-instar larvae than in other life stages.

[Analysis of risk factors of ventilator-associated pneumonia in an intensive care unit].

Objective: To explore the risk factors of ventilator-associated pneumonia (VAP) in patients admitted in an intensive care unit (ICU) for pulmonary tuberculosis (TB).

Methods: The clinical data of 143 patients admitted in the ICU at our center between January, 2014 and June, 2015 were reviewed. The patients with VAP and those without VAP were analyzed for risk factors of VAP in the setting of an ICU for pulmonary TB and compared for the duration of ventilation and hospital stay.

[The clinical significance of changes in CD4+ T cell counts by peripheral blood from patients with pulmonary tuberculosis after antitubercular treatment].

Aim: To explore the clinical significance of changes in CD4+ T cell counts by peripheral blood from patients with pulmonary tuberculosis after antitubercular treatment.

Methods: CD4+ T cell counts in the peripheral blood of 62 pulmonary TB patients were counted by flow cytometry from groups auording to the radiologic extent of disease, and compared with those obtained from 30 controls.

Results: (1) The baseline levels of CD4+ T cell counts (439.

[A retrospective study of one case of X-linked agammaglobulinemia].

Objective: To investigate the clinical manifestations, diagnostic methods and treatment of X-linked agammaglobulinemia (XLA).

Methods: Flow cytometric analysis of the peripheral monocytes using the anti-BTK antibody was used to characterize the expression of BTK in a 21 year old male patient and his mother. The patient suffered from frequent pneumonia, and was found to be complicated with lymphocytopenia in the B cell populations, hypogammaglobulinemia (IgG 1.

[Photoxidation reaction of Tl(I) in surface water].

The valence state of thallium affecting its toxicity, distribution and mobility, photoxidation reaction of Tl(I) was studied under the radiation from high-pressure arc mercury light or solar light. The results show that the low pH, the strong light intensity and UVB and VUC region are in favor of the photoxidation of Tl(I). In the case of pH = 2, only less than 1% Tl(I) remained in the solution after 10 min of irradiation, while pH = 9, with about 83% Tl(I) in the solution after 1 h of irradiation.

[Comparison of paclitaxel and carboplatin versus ifosfamide, etoposide, and carboplatin regimen for treatment of patients with advanced non-small cell lung cancer].

Background And Objective: The platinum-containing combination chemotherapy has been proved to be benefit to the patients with advanced non-small cell lung cancer. Compared with cisplatin-based combination chemotherapy regimens, carboplatin-based regimens result in longer survival time and less toxicity, despite of lower response rate. In the palliative treatment setting, less toxicity and longer survival may be more significant than response rate.