Publications by authors named "De-sheng Meng"
Article Synopsis
- Hypericin (HY) is highlighted as a strong photosensitizer for photodynamic therapy (PDT) in treating port-wine stains, which are congenital skin conditions caused by faulty blood vessels.
- In experiments, HY demonstrated notable effectiveness in hindering the growth of human vascular endothelial cells (HUVECs) and inducing apoptosis (cell death) more efficiently than another photosensitizer, hematoporphyrin (HP).
- Additionally, studies using a chicken cockscomb model confirmed HY's photocytotoxic effects, characterized by significant changes in mitochondrial structure and increased release of cytochrome c, signaling its potential as a highly effective treatment option for PWS.
Objective: To observe the influence on prognosis and possible side-effects of arginine in
Methods: Multi-center clinical trial, randomized double blinded patients with severe trauma and burns. and placebo control methods were employed in the study. Eighty-six patients with severe trauma and burns were randomly divided into control (C, n = 45) and arginine treatment (Arg, n = 41) groups.
[The changes in the prostaglandin level and the prostaglandin transfer factor mRNA expression in the intestinal mucosa in scalded rats].
Zhonghua Shao Shang Za Zhi
October 2003
Objective: To explore the changes in the PGE(2) and PGI(2), TXA(2) levels and PGT mRNA expression in the intestinal mucosa in scalded rats.
Methods: Wistar rats inflicted with TBSA 30% III degree scald were employed as the model. The PGE(2) and PGI(2) and TXA(2) contents in the intestinal mucosa were measured by radioimmunoassay, and the expression of PGT mRNA was detected by in situ hybridization.