Publications by authors named "De-qing Xu"
Chin Med J (Engl)
July 2004
Article Synopsis
- Skin lesions in systemic lupus erythematosus (SLE) are common, but the exact cause and role of DNA in these lesions remains unclear; this study investigates this relationship.
- The researchers examined skin samples from SLE patients and used various methods to analyze extracellular DNA found in the lesions, discovering that DNA was only present in affected skin areas, not in normal or non-lesion skin.
- Results indicated that DNA fragments correlated with disease activity, suggesting that DNA and immune complexes play a role in the development of skin lesions in SLE, with significant homology to human DNA, but not microbial DNA.
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