Publications by authors named "De-Xuan Gao"
The aim of this study was to observe the effects of bone marrow mesenchymal stem-cell transplantation (BMSCs) in repairing acute spinal cord damage in rats and to examine the potential beneficial effects. 192 Wistar rats were randomized into 8 groups. Spinal cord injury was created.
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- Immune cells, particularly regulatory T cells (Tregs), influence angiogenesis in renal cell carcinoma (RCC), a highly vascular tumor.
- Increased Tregs were found in the blood and tumors of RCC patients compared to healthy controls, correlating with tumor progression and angiogenic markers like VEGF.
- The study highlights a significant relationship between tumor-infiltrating Tregs and the tumor's angiogenic activity, suggesting Tregs may play a role in enhancing RCC's vascular development.
Objective: To evaluate the roles of total prostate specific antigen (tPSA), PSA density (PSAD) and biopsy Gleason score in predicting the pathologic stage of prostate cancer.
Methods: We retrospectively analyzed the clinical data of 124 cases of pathologically confirmed prostate adenocarcinoma, and divided them into Groups A (n=48) and B (n=76) based on the results of bone scanning, CT, MRI, tPSA, PSAD and postoperative biopsy Gleason score, the former with extraprostatic infiltration or distant metastasis, while the latter without. We compared the above parameters between the two groups, screened the main factors that influenced the pathologic staging of prostate cancer by multivariate logistic regression analysis, and appraised the value of each of the parameters in predicting the pathologic stage of prostate cancer with a relative operating characteristic (ROC) curve.
[An analysis for the phenotype and genotype of autosomal dominant polycystic kidney disease from two Chinese families].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
February 2006
Objective: To scan for mutations of polycystic kidney disease 1 gene (PKD1) in Chinese population in order to find some features about Chinese patients and a better approach to detect mutations.
Methods: Twenty-five PKD-affected individuals from twenty-one unrelated genealogies and sixteen controls participated in the study. Thirty-five blood samples and six tissues were obtained after receiving informed consent and were in accordance with institutional ethical guidelines.