Publications by authors named "De-Shi Shi"
Background: Streptococcus suis is an important swine pathogen and zoonotic agent. Infection with this highly pathogenic strain can cause streptococcal toxic shock-like syndrome (STSLS), characterized by a Th-1 inflammatory cytokine storm, and a high mortality rate. Monocyte derived dendritic cells (MoDCs) are known to stimulate Th-1 cell differentiation, but the role of MoDCs in STSLS remains to be elucidated.
View Article and Find Full Text PDF[Induction or inhibition of apoptosis by pseudorabies virus ea strain in suckling piglets].
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
April 2003
Article Synopsis
- The study examines how the pseudorabies virus (PrV) affects apoptosis (cell death) in suckling piglets, focusing on the Ea strain of the virus.
- Various tissue samples were collected from infected piglets, and several methods like electron microscopy and TUNEL staining were used to identify apoptotic cells.
- It was found that the PrV infection primarily induced apoptosis in lymphoid tissues, weakening the immune system and leading to the death of piglets, while establishing a latent infection in nerve tissues by preventing apoptosis in those cells.