[Establishment of an animal model of infection and study on therapeutic methods Ⅰ Establishment of an animal model of infection in mice and changes of serum specific antibody levels post-infection].

Objective: To establish an animal model of (plerocercoid larva of ) infection in mice and observe the changes of blood routine examinations and serum anti-sparganum antibody levels after the infection.

Methods: The spargana tapeworms were collected from frogs, and 25 Kunming mice were orally infected with the tapeworms (3 tapeworms/mouse). Two days before the infection and 2, 7, 14, 21, 28, 35, 42 days and 49 days after the infection, the peripheral blood samples of mice were collected for the blood routine examinations and the detections of anti- IgG antibody with ELISA.

[Clinical analysis of 17 cases of paragonimiasis].

Objective: To investigate the clinical features, diagnosis and treatment of paragonimiasis, so as to improve the prevention and treatment of it.

Methods: The clinical data of paragonimiasis patients were collected and retrospectively analyzed.

Results: Totally 17 patients were diagnosed as paragonimiasis and the main clinical features of 11 patients were cough, chest pain and fever, and the pleural effusion was found in 13 cases.

[Detection of four parasitic infections using ELISA].

Objective: To study the detection effects of ELISA for the infections of Cysticercus, Echinococcosus, Paragonimus westermani and Sparganum mansoni in order to improve diagnosis.

Methods: The patients who admitted to Jiangsu Institute of Parasitic Diseases from 2008 to 2001 were selected as the subjects and their sera were detected for IgG against Cysticercus, Echinococcosus, and Paragonimus westermani from January 2008 to March 2011, and IgG against Sparganum mansoni since June, 2011 by ELISA.

Results: A total of 282 cases were detected, and 88 of them were found one or two positive results, and the total positive rate was 31.

[Spirometra mansoni infection in an infant: one case report].

This paper reports the diagnosis and therapy of one case of Spirometra mansoni infection in an infant.

[Diagnosis and treatment of one patient infected with Thelazia callipaeda].

This paper reports the diagnosis and treatment of one patient infected with Thelazia callipaeda, which suggests that in the diagnosis, the ophthalmologists should combine the epidemiological contact history with the examination so as to avoid misdiagnosis.

[Hookworm infection post-rectal cancer surgery: one case report].

A patient with hookworm infection post-rectal cancer surgery was detected. After the helminthic and iron-supplement treatment, the patient' s condition improved.

[Serological investigation on Toxoplasma gondii infection in dialysis patients with renal insufficiency].

A total of 205 dialysis patients with renal insufficiency were selected as an experiment group, and 360 healthy people were selected as a control group. The specific IgG antibodies of Toxoplasma gondii of the objects in the 2 groups were detected by ELISA. The positive rates of the experiment and control groups were 27.