Dose-response relationship between risk factors and incidence of COVID-19 in 325 hospitalized patients: A multicenter retrospective cohort study.

Background: The epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) patients have been widely reported, but the assessment of dose-response relationships and risk factors for mortality and severe cases and clinical outcomes remain unclear.

Aim: To determine the dose-response relationship between risk factors and incidence of COVID-19.

Methods: In this retrospective, multicenter cohort study, we included patients with confirmed COVID-19 infection who had been discharged or had died by February 6, 2020.

Microvascular invasion and positive HB e antigen are associated with poorer survival after hepatectomy of early hepatocellular carcinoma: A retrospective cohort study.

Background: We aimed to identify the independent predictive factors of microvascular invasion (MVI) for curative resection of HCC and to investigate the impacts of MVI and HBeAg on long-term recurrence and survival after resection.

Methods: The clinicopathological parameters of 237 patients with HCC with MVI who underwent hepatic resection from April 2005 to November 2010 were investigated. Clinical features and factors associated with the clinical outcomes of 386 patients with HCC without MVI were used for comparison.

Overexpression of long non-coding RNAs DUXAP9 and DUXAP10 is associated with prognosis in patients with hepatocellular carcinoma after hepatectomy.

Aim: Hepatocellular carcinoma (HCC) is a common and aggressive malignant tumor with an especially high prevalence in Asian populations. This study aimed to identify differentially expressed lncRNAs using expression microarray and to explore the association between differential expression of lncRNAs and prognosis of HCC.

Methods: We retrospectively reviewed 63 patients with primary HCC that underwent a curative liver resection at the Department of General Surgery, Jingmen First People's Hospital.

MeCP2 level is associated with hepatocellular carcinoma development in chronic hepatitis B patients under antiviral therapy.

Aim: Hepatocellular carcinoma (HCC) is a common and aggressive malignant tumor with especially high prevalence in Asia. This present study aimed to investigate the association of MeCP2 with HCC development in patients with undetectable HBV DNA by antiviral therapy.

Methods: We retrospectively reviewed the 258 patients that were recruited into the present study.

Partial hepatectomy for spontaneous tumor rupture in patients with hepatocellular carcinoma: a retrospective cohort study.

Background: The impact of ruptured hepatocellular carcinoma (HCC) on a patients outcome after hepatic resection remains insufficient. We aimed to identify the independent predictive factors of spontaneous tumor rupture (STR) for curative resection of HCC and to investigate the impact of STR of HCC on long-term survival after resection.

Patients And Methods: The clinicopathological parameters of 106 patients with ruptured HCC and 201 patients with non-ruptured HCC who underwent hepatic resection from 2007 to 2011 were investigated.

Exosomal miR-9-3p suppresses HBGF-5 expression and is a functional biomarker in hepatocellular carcinoma.

Background: Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading cause of cancer-related death worldwide. Exosomes are secreted membrane vesicles that play important roles in various diseases by transporting proteins and RNAs, including microRNAs, between cells. However, the function of exosomal miRNA in HCC has not been fully investigated.

Hepatogenic differentiation from human adipose-derived stem cells and application for mouse acute liver injury.

Adipose-derived stem cells (ADSCs) derived from adipose tissue have the capacity to differentiate into endodermal, mesoderm, and ectodermal cell lineages in vitro, which are an ideal engraft in tissue-engineered repair. In this study, human ADSCs were isolated from subcutaneous fat. The markers of ADSCs, CD13, CD71, CD73, CD90, CD105, CD166, CYP3A4, and ALB were detected by immunofluorescence assays.

[Scale-dependency of spatial variability of surface soil moisture under different land use types in Heihe Oasis, China].

To study the surface soil moisture spatial variability and its scale effect is of significance to understand the real variability of soil moisture and to objectively provide a reference for constructing a logical sampling scheme. By using "re-sampling" method, this paper studied the scale-dependency of the spatial variability of soil surface moisture in the woodland and farmland in the oasis ecological system in the middle reaches of Heihe River. The results showed that the variation degree of the surface soil moisture in the test woodland and farmland increased with increasing soil moisture content, and the coefficient of variation (CV) became closer to the true value when the sampling scale increased.