Synopsis of recent research by authors named "De-Jian Huang"
- De-Jian Huang's research focuses on the pharmacological effects of flavones, particularly luteolin, and their modified derivatives, which demonstrate enhanced protective mechanisms against myocardial ischemia/reperfusion injury and inflammation by avoiding methylation by catechol-O-methyltransferase (COMT).
- His studies also explore the cardiotoxic effects of doxorubicin, highlighting the reduction of Na+/K+ ATPase activity and the involvement of ferroptosis in doxorubicin-induced cardiotoxicity.
- Huang's earlier work has examined various cardiovascular risk factors, such as pericardial adipose tissue volume and the biochemical roles of hydrogen sulfide and nitric oxide, contributing to the understanding of cardiovascular diseases and complications.