The role and mechanism of biological collagen membranes in repairing cartilage injury through the p38MAPK signaling pathway.

Objective: To explore the mechanism of the p38MAPK signaling pathway in repairing articular cartilage defects with biological collagen membranes.

Methods: Thirty-two healthy adult male rabbits were randomly divided into a control group (n = 8), model group (n = 8), treatment group (n = 8) and positive drug group (n = 8). The control group was fed normally, and the models of bilateral knee joint femoral cartilage defects were established in the other three groups.