Publications by authors named "De-Guang Kong"

Article Synopsis
  • Mumps outbreaks have been increasingly reported globally, including in vaccinated populations, prompting a study on the epidemic's characteristics in Wuhan from 2005 to 2019.
  • The study analyzed 40,685 mumps cases, revealing a fluctuating morbidity rate with significant peaks every few years and highlighted a bimodal seasonal pattern, predominantly affecting male children aged 5-9.
  • Findings indicated spatial clusters of high cases primarily in the western and southern regions of Wuhan, helping public health officials improve targeted health strategies and resource allocation.
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The immense patient number caused by coronavirus disease 2019 (COVID-19) global pandemic brings the urge for more knowledge about its immunological features, including the profile of basic immune parameters. In this study, eighty-eight reported COVID-19 patients in Wuhan were recruited from January to February, 2020, including 32 severe/critical cases and 56 mild/moderate cases. Their mean age was 56.

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Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first reported in Wuhan, Hubei Province, China in late December 2019. We re-analysed 640 throat swabs collected from patients in Wuhan with influenza-like-illness from 6 October 2019 to 21 January 2020 and found that 9 of the 640 throat swabs were positive for SARS-CoV-2 RNA by quantitative PCR, suggesting community transmission of SARS-CoV2 in Wuhan in early January 2020.

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A gastroenteritis outbreak occurred in a university in May, 2017, Wuhan, China. The epidemiological survey and pathogen analysis were conducted to identify the pathogen and control this outbreak. Feces or anal swabs from individuals, water, and swabs taken from tap surfaces of the secondary water supply system (SWSS) and foods were collected for the detection of viruses and pathogenic enteric bacteria by real-time RT-PCR and culture, respectively.

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Hepatitis E virus (HEV) is an emergent virus of global importance. Previous studies of HEV infection in China mainly focused on the rural areas. This work aims to study the epidemiology of HEV in a large urban environment.

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Article Synopsis
  • * Researchers developed a seasonal ARIMA model to analyze 84 months of HFMD data (2009-2015) for forecasting future incidences, which showed effective predictions with clear pattern recognition.
  • * The identified optimal ARIMA model (1,0,1)(0,1,1) demonstrated strong predictive capabilities, highlighting two peaks of HFMD activity in mid-year and late-year, and emphasizes the need for continual updates to the model for improved future forecasts.
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In 2014, 20 dengue cases were reported in the cities of Wenzhou (5 cases) and Wuhan (15 cases), China, where dengue has rarely been reported. Dengue virus 1 was detected in 4 patients. Although most of these cases were likely imported, epidemiologic analysis provided evidence for autochthonous transmission.

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