[An efficient method for simulating ventricular electrical activity based on anatomic structure by incorporating AP model].

Conventional medical experiments can hardly simulate cardiac excitation propagation and observe the evolvement of cardiac electrical activities firsthand as is possible with computer simulation. Based on the anatomic structure of the heart, simulation of cardiac electrical activity mainly consists of the emulation of the excitation process among the cardiac cells and calculation of the electrical activities of individual cardiac cells. In this study we establish a geometric ventricular structure model demonstrating the direction of the cardiac muscle fibers and the layers of the ventricular cells, and endow different action potential models to the ventricular cells of different layers, and observe the activation process of the ventricular parts in view of the three-dimensional anatomy.

[Study on distribution of cardiac electric field around the isolated heart of guinea pig].

Objective: To define the distribution of the cardiac electric field around the isolated heart of guinea pig.

Methods: The hearts of 26 guinea pigs were isolated and immersed in normal saline or distilled water, and the ECGs were recorded in 4 directions of every plane with 4 points deposited in every direction at different distances from the anterior, posterior and the laterals of both the ventricles of the heart.

Result: In both media, ECGs were composed mainly of upright waves were recorded at all points in the 4 directions at the 3 levels.