Significant elevation of serum caspase-3 levels in patients with intracerebral hemorrhage.

Background: Caspase-3 is a potential marker of apoptosis. We investigated whether serum caspase-3 concentrations were increased and its association with severity and prognosis after intracerebral hemorrhage (ICH).

Methods: This prospective clinical study recruited 112 ICH patients and 112 healthy individuals.