Effects of prior anterior cruciate ligament reconstruction on clinical outcomes associated with total knee arthroplasty: A protocol of retrospective analysis.

Background: The argument on the clinical effects of previous anterior cruciate ligament (ACL) reconstruction on total knee arthroplasty (TKA) remains to be resolved. The aim of the current study was to compare operative and postoperative outcomes of patients undergoing TKA after ACL reconstruction with a matched cohort of control subjects having primary osteoarthritis and no history of ligament reconstruction.

Methods: This study was performed and reported in accordance with the Strengthening the Reporting of Observational studies in Epidemiology checklist.

[Therapeutic effects of Bianyanning decoction on acute pharyngitis in rats and its mechanism].

Objective: To investigate the therapeutic effects and mechanisms of Bianyanning on acute pharyngitis in rats, and to provide evidence and experimental data for its clinical application.

Methods: The acute pharyngitis of rats was induced by spraying ammonia directly to their throat. The model rats were randomly divided into model control group, the high-, medium- and low-dose group of Bianyanning, while normal rats were used as control group, 10 in each group.

maxim extract attenuates abnormal Tau phosphorylation.

Large-scale epidemiological studies have found that hyperhomocysteinemia is a powerful, independent risk factor for Alzheimer's disease. Trillium tschonoskii maxim is a traditional Chinese medicine that is used to promote memory. However, scientific understanding of its mechanism of action is limited.