Recently, the issue of electromagnetic pollution has become increasingly prominent. Flexible polymer films with various conductive fillers are preferred to address this problem due to their highly efficient and durable electromagnetic interference (EMI) shielding performance. However, their applications are restricted by the unbalanced and insufficient electromagnetic wave absorption and shielding capabilities, as well as the weak interlayer bonding force.
View Article and Find Full Text PDFMaterials (Basel)
September 2024
Pursuing improved electrode materials is essential for addressing the challenges associated with large-scale Li-ion battery applications. Specifically, silicon oxide (SiO) has emerged as a promising alternative to graphite anodes, despite issues related to volume expansion and rapid capacity degradation. In this study, we synthesized carbon-coated SiO using diatom biomass derived from artificially cultured diatoms.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2024
Foodborne illnesses caused by Salmonella bacteria pose a significant threat to public health. It is still challenging to detect them effectively. Herein, biotemplated Janus disk-shaped magnetic microrobots (BJDMs) based on diatomite are developed for the highly efficient detection of Salmonella in milk.
View Article and Find Full Text PDFRapid biological detection of pathogen micro-organisms has attracted much attention for practical biomedical applications. Despite the development in this field, it is still challenging to achieve simple and rapid biological detection using the microfluidic method. Herein, we propose a novel strategy of biological detection that combines precise detection control of the capillary microfluidic chip and versatile manipulation of magnetic beads.
View Article and Find Full Text PDFACS Appl Mater Interfaces
May 2024
Magnetic micro/nanorobots are promising platforms for targeted drug delivery, and their construction with soft and flexible features has received extensive attention for practical applications. Despite significant efforts in this field, facile fabrication of magnetic microrobots with flexible structures and versatility in targeted therapy remains a big challenge. Herein, we proposed a novel universal strategy to fabricate a biohybrid flexible sperm-like microrobot (BFSM) based on a (.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
February 2024
Nanostructured silica-based materials have great potential as drug delivery vehicles for precise and personalized medical applications. As natural nanostructured silica, diatomite biosilica (DB) is recognized as a novel carrier to construct oral/parenteral smart drug delivery systems due to high surface area, biocompatibility, and applicability at low cost, yet the related studies on its use in local delivery routes are still scarce. Herein, we proposed a novel strategy to develop multifunctional nasal drug delivery vehicles based on DB, and demonstrated their versatile performance for enhanced treatment of allergic rhinitis (AR).
View Article and Find Full Text PDFIntroduction: There is no uniform classification standard for brain stem haemorrhage. On the basis of previous experience in the treatment of brainstem haemorrhage, this study explored and established a set of criteria for brainstem haemorrhage classification, risk-stratified such patients and guided the selection of treatment options so as to achieve accurate and standardized diagnosis and treatment.
Material And Methods: Thirty patients with brainstem haemorrhage from April 2019 to May 2022 were included.
Microorganisms have attracted much attention to act as biotemplates for fabricating micro/nanostructured functional particles. However, it is still challenging to produce tunable hierarchical particles based on microorganisms with intricate architectures and superior stability. Herein, a novel strategy is developed to fabricate biohybrid urchin-like magnetic ZnO microspheres based on Chlorella (Ch.
View Article and Find Full Text PDFFlexible composite films have attracted considerable attention due to great potential for healthcare, telecommunication, and aerospace. However, it is still challenging to achieve high conductivity and multifunctional integration, mainly due to poorly designed composite structures of these films. Herein, a novel sandwich-structured assembly strategy is proposed to fabricate flexible composite thin films made of Ag nanowire (AgNW) core and MXene layers by combination of spray coating and vacuum filtration process.
View Article and Find Full Text PDFBackground: Dementia is a growing public health concern worldwide. Community residents still have limited knowledge about dementia prevention, although many sources are accessible for individuals to acquire knowledge.
Methods: A questionnaire-based survey was conducted in five communities in Chongqing, China, between March 2021 and February 2022.
We successfully prepared highly anisotropic conductive composites (ACCs) made of Ag-coated glass microbeads/UV adhesive via electric field-induced alignment, which was achieved using custom patterned microelectrode arrays. An optimized AC electric field (2 kV/cm, 1 kHz) with pole-plate spacing (50 μm) was utilized to effectively assemble the microbeads into chain arrays, which were precisely positioned on the microelectrode arrays to construct ordered conductive channels. In this case, tangling and cross-connection of the assembled microchains could be reduced, resulting in enhanced performance of the ACCs with high conductivity as well as excellent anisotropy.
View Article and Find Full Text PDFFlexible pressure sensors have attracted much attention due to their significant potentials in E-skin, artificial intelligence, and medical health monitoring. However, it still remains challenging to achieve high sensitivity and wide sensing range simultaneously, which greatly limit practical applications for flexible sensors. Inspired by the surface stress-induced structure of mimosa, we propose a novel flexible sensor based on the carbon nanotube paper film (CNTF) and stress-induced square frustum structure (SSFS) and demonstrated their excellent sensing performances.
View Article and Find Full Text PDFBackground: Lifestyle factors may could help maintain cognitive function and reduce the risk of dementia. The application of the Health Belief Model (HBM) has been verified by incorporating lifestyle changes for dementia risk reduction; however, the influence of health beliefs on cognitive aging through lifestyle remains unknown. To facilitate research-based interventions to promote successful cognitive aging, we explored the relationship between health beliefs, lifestyle, and cognitive aging based on the HBM using path analysis.
View Article and Find Full Text PDFBiosens Bioelectron
February 2023
Stretchable strain sensors based on nanomaterial thin films have aroused extensive interest for the strain perception of smart skins. However, it still remains challenging to have them achieve high sensitivity over wide linear working ranges. Herein, we propose a facile strategy to fabricate stretchable strain sensors based on Au/graphene composite films (AGCFs) with hierarchical cracks and demonstrate their superior sensing performances.
View Article and Find Full Text PDF2D layered molybdenum disulfide (MoS ) nanomaterials are a promising platform for biomedical applications, particularly due to its high biocompatibility characteristics, mechanical and electrical properties, and flexible functionalization. Additionally, the bandgap of MoS can be engineered to absorb light over a wide range of wavelengths, which can then be transformed into local heat for applications in photothermal tissue ablation and regeneration. However, limitations such as poor stability of aqueous dispersions and low accumulation in affected tissues impair the full realization of MoS for biomedical applications.
View Article and Find Full Text PDFBackground: Existing evidence-based guidelines and summaries on dementia prevention are not effectively disseminated and used by primary health care workers in developing countries. As such, the lack of knowledge and skills is a major obstacle to dementia prevention and has posed a need for relevant training.
Objectives: To evaluate the effects of an Internet-based dementia-related training program with the aim to improve the competence of primary health care workers to early detection of symptoms of memory disorder and dementia, and to provide effective guidance and consultation for residents.
ACS Appl Mater Interfaces
February 2022
Magnetic micro-/nanorobots have been regarded as a promising platform for targeted drug delivery, and tremendous strategies have been developed in recent years. However, realizing precise and efficient drug delivery in vivo still remains challenging, in which the versatile integration of good biocompatibility and reconfiguration is the main obstacle for micro-/nanorobots. Herein, we proposed a novel strategy of magnetic biohybrid microrobot multimers (BMMs) based on (.
View Article and Find Full Text PDFSperm cells can move at a high speed in biofluids based on the flexible flagella, which inspire novel flagellar micro-/nanorobots to be designed. Despite progress in fabricating sperm-type robots at micro scale, mass fabrication of vivid sperm-like nanorobots with flagellar flexibility is still challenging. In this work, a facile and efficient strategy is proposed to produce flexible sperm-like nanorobots with self-assembled head-to-tail structure, and its bidirectional propulsion property was studied in detail.
View Article and Find Full Text PDFACS Appl Mater Interfaces
November 2021
Wastewater remediation toward heavy metal pollutants has attracted considerable attention, and various adsorption-based materials were employed in recent years. However, it is still challenging to explore low-cost and high-efficient adsorbents with superior removal performance, nontoxicity, flexible operation, and good reusability. Herein, FeO- and MnO-loaded biohybrid magnetic helical microrobots (BMHMs) based on cells were presented for the first time, and their performance on Pb(II) removal was studied in detail.
View Article and Find Full Text PDFMicromachines (Basel)
August 2021
Diatom frustules are a type of natural biomaterials that feature regular shape and intricate hierarchical micro/nano structures. They have shown excellent performance in biosensing, yet few studies have been performed on flow-through detection. In this study, diatom frustules were patterned into step-through holes and bonded with silicon substrate to form an open-ended filtration array.
View Article and Find Full Text PDFAims And Objectives: To determine the aspects of excretory dysfunction most influential in determining the quality of life of survivors of spinal cord injury.
Background: Excretory dysfunction is one of the most common and troublesome sequelae of spinal cord injury. Previous studies have shown that it can restrict social participation restriction, cause readmission and generally influence quality of life substantially.
Background: Massive open online courses (MOOCs) are innovative courses that have aroused great interest in the field of nursing education. However, most studies have focused only on the benefits of MOOCs rather than the issues and how to ameliorate them.
Objectives: To compare the differences between the "blended learners" (who studied at a university and via a MOOC) and "social learners" (MOOC-only learners) in course completion, participation, performance, and online interactions.
ACS Appl Mater Interfaces
February 2019
Magnetic microrobots can be actuated in fuel-free conditions and are envisioned for biomedical applications related to targeted delivery and therapy in a minimally invasive manner. However, mass fabrication of microrobots with precise propulsion performance and excellent therapeutic efficacy is still challenging, especially in a predictable and controllable manner. Herein, we propose a facile technique for mass production of magnetic microrobots with multiple functions using Spirulina ( Sp.
View Article and Find Full Text PDFCTL lyse target cells through the release of cytolytic granule mediators and expression of the death receptor ligand Fas ligand (FasL). We previously demonstrated that FasL is stored in vesicles distinct from cytolytic granules and is translocated to the cell surface within 15 min of TCR stimulation, followed by a later wave of newly synthesized FasL cell surface expression at 2 h poststimulation. Initial studies suggested that the two FasL responses had different signaling thresholds.
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