Publications by authors named "Dayshaun J Dennis"
Pharmacol Res
January 2021
Article Synopsis
- - Mitochondrial dysfunction is a key early feature in major neurodegenerative diseases like Alzheimer's and Parkinson's, characterized by issues such as increased cell death and energy mismanagement.
- - Inorganic polyphosphate (polyP) is a conserved molecule that regulates mitochondrial function and may serve as an alternative energy source to ATP, potentially impacting calcium and protein balance within mitochondria.
- - The review highlights polyP as a promising pharmacological target to combat mitochondrial dysfunction in neurodegenerative disorders, while emphasizing the need for further research to clarify its role and effects.
