Systemic Bevacizumab for Treatment of Respiratory Papillomatosis: International Consensus Statement.

Objectives/hypothesis: The purpose of this study is to develop consensus on key points that would support the use of systemic bevacizumab for the treatment of recurrent respiratory papillomatosis (RRP), and to provide preliminary guidance surrounding the use of this treatment modality.

Study Design: Delphi method-based survey series.

Methods: A multidisciplinary, multi-institutional panel of physicians with experience using systemic bevacizumab for the treatment of RRP was established.

First Clinical Consensus and National Recommendations on Tracheostomized Children of the Brazilian Academy of Pediatric Otorhinolaryngology (ABOPe) and Brazilian Society of Pediatrics (SBP).

Introduction: Tracheostomy is a procedure that can be performed in any age group, including children under 1year of age. Unfortunately health professionals in Brazil have great difficulty dealing with this condition due to the lack of standard care orientation.

Objective: This clinical consensus by Academia Brasileira de Otorrinolaringologia Pediátrica (ABOPe) and Sociedade Brasileira de Pediatria (SBP) aims to generate national recommendations on the care concerning tracheostomized children.

Salivary gland surgery for control of chronic pulmonary aspiration in children with cerebral palsy.

Objective: To evaluate the outcome of surgical saliva reduction to decrease pulmonary aspiration in children with cerebral palsy and its repercussions in respiratory infection control.

Methods: Twenty-nine children with neurological impairment and diagnosis of chronic pulmonary aspiration were submitted to bilateral submandibular gland excision and bilateral parotid duct ligation at the Association for the Welfare of Physically Handicapped Children, from December 2001 to December 2004. Postoperative frequency of lower respiratory tract infection, hospitalization rate due to pulmonary infection and airway secretion level after the surgery were compared to preoperative period.

Postoperative acute respiratory insufficiency following adenotonsillectomy in children with neuropathy.

Objective: Evaluate the incidence of acute respiratory insufficiency (ARI) in the immediate postoperative period following adenotonsillectomy in children with neurological diseases.

Methods: Medical records from all pediatric adenotonsillectomies performed from January 1997 through August 2003 at the Roberto de Abreu Sodré Hospital of the Association for the Welfare of Physically Handicapped Children (AACD) in São Paulo were reviewed. Data were collected for patient age, neurological diagnosis, associated comorbidities, index of respiratory insufficiency in the immediate postoperative period and period of hospitalization.

Drooling: analysis and evaluation of 31 children who underwent bilateral submandibular gland excision and parotid duct ligation.

Aim: To evaluate the safety of bilateral submandibular gland excision and parotid duct ligation in order to control drooling in children; to assess its long-term efficacy and complications.

Study Design: longitudinal cohort.

Materials And Methods: Thirty-one children aged 6 to 13 years (7.

Surgery for aspiration: analysis of laryngotracheal separation in 23 children.

The aim of this study was to analyze the efficacy of laryngotracheal separation (LTS) in eliminating aspiration in children by comparing pre- and postoperative conditions. This prospective study used an internal control group. Children with neurologic impairment and a diagnosis of chronic aspiration were subjected to LTS at the Associação de Assistência à Criança Deficiente (AACD).

Application of botulinum toxin to reduce the saliva in patients with amyotrophic lateral sclerosis.

Aim: To demonstrate the effect of local application of Botox(R) in patients with amyotrophic lateral sclerosis (ALS), following our 2002 institutional protocol of sialorrhea treatment.

Study Design: Clinical prospective.

Material And Method: Five patients with ALS assisted at Clinic of Otolaryngology of AACD (Associação de Assistência à Criança Deficiente).

[Fiberoptic endoscopic swallowing disorders in chronic encephalopathy].

OBJECTIVE: To evaluate the results of fiberoptic endoscopic examination of swallowing safety in children with cerebral encephalopathy in order to identify patients with oropharyngeal dysphagia. METHODS: 68 children from the Association for the Care of Disabled Children (Associação de Assistência à Criança Deficiente -AACD), São Paulo, were submitted to fiberoptic endoscopic examination of swallowing safety from March 1999 to March 2000. RESULTS: We observed premature spillage (53%), penetration in a pureed consistency (5.