Publications by authors named "Dayeong Bae"
Diagnosing malaria using standard techniques is time-consuming. With limited staffing in many laboratories, this may lead to delays in reporting. Innovative technologies are changing the diagnostic landscape and may help alleviate staffing shortages.
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- The White Blood Cell (WBC) differential test is a commonly used diagnostic tool that involves expert analysis of blood samples to identify abnormalities.
- Automated digital microscopy offers a more efficient alternative to manual inspections, though it faces challenges with capturing high-quality images due to the need for multiple focal planes.
- A new dataset of 25,773 image stacks from 72 patients has been created, featuring 18 cell classes (both normal and abnormal), which has been meticulously labeled by experts to support advanced WBC classification using machine learning techniques.
RNase E is an essential enzyme in Escherichia coli. The cleavage site of this single-stranded specific endoribonuclease is well-characterized in many RNA substrates. Here, we report that the upregulation of RNase E cleavage activity by a mutation that affects either RNA binding (Q36R) or enzyme multimerization (E429G) was accompanied by relaxed cleavage specificity.
View Article and Find Full Text PDFAptamers are short single-stranded DNA or RNA oligonucleotides capable of binding with high affinity and specificity to target molecules. Because of their durability and ease of synthesis, aptamers are used in a wide range of biomedical fields, including the diagnosis of diseases and targeted delivery of therapeutic agents. The aptamers were selected using a process called systematic evolution of ligands by exponential enrichment (SELEX), which has been improved for various research purposes since its development in 1990.
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