Optimization of Extraction Conditions for Improving Gallic Acid and Quercetin Content in Fruits: A Promising Cosmetic Ingredient.

, also known as cutite, is an Amazonian fruit distributed in the western regions of North Brazil. Its fruits are rich in phenolic compounds, such as gallic acid (GA) and quercetin (Q), making it an excellent ingredient for cosmetic applications due to its high antioxidant activity and stability. A study optimized the extraction of GA and Q using hydroalcoholic ultrasound-assisted extracts by a central composite design, focusing on three independent variables: water-ethanol percentage (%HO; v/v), fruit-solvent ratio (FSR; w/v), and time (; min).