Publications by authors named "Dayang Huang"
Transseptal Sheath Perfused With High Concentration Heparinized Saline for Reducing Sheath-Associated Thrombus.
Pacing Clin Electrophysiol
March 2025
Article Synopsis
- The study focused on the use of transseptal sheaths (TSS) for atrial fibrillation (AF) ablation, aiming to prevent thromboembolism through a simple saline flush management technique.
- In the retrospective study involving over 4,700 AF patients, complications were low, with no acute strokes, and only a few thromboembolic issues occurring post-procedure.
- The prospective study showed no thrombus formation in 127 procedures using high concentration heparinized saline, demonstrating that this method is both safe and effective for preventing thrombus during AF radiofrequency ablation.
Lipid droplets (LDs) are cellular organelles critical for lipid homeostasis, with intramyocyte LD accumulation implicated in metabolic disorder-associated heart diseases. Here we identify a human long non-coding RNA, Lipid-Droplet Transporter (LIPTER), essential for LD transport in human cardiomyocytes. LIPTER binds phosphatidic acid and phosphatidylinositol 4-phosphate on LD surface membranes and the MYH10 protein, connecting LDs to the MYH10-ACTIN cytoskeleton and facilitating LD transport.
View Article and Find Full Text PDFAcute conduction recurrence of mitral isthmus: Incidence, clinical characteristics, and implications.
Pacing Clin Electrophysiol
December 2020
Background: Data on the incidence, clinical characteristics, and implications of acute conduction recurrence during mitral isthmus (MI) ablation are scarce.
Methods: MI ablation was performed in patients with atrial fibrillation. After confirming bidirectional conduction block, the acute conduction recurrence of MI was systematically evaluated.
Background: Some studies on the relationship between LINC00673 polymorphism and cancer susceptibility have been inconsistent. To perform a more comprehensively quantitative assessment of LINC00673 rs11655237 and risk of overall cancer, we operated this meta-analysis for the first time.
Methods: A comprehensive search was conducted to obtain relevant literature up to November 20, 2019.
Aims: Phospholamban (PLB) stoichiometrically regulates the cardiac Ca pump (SERCA2a) in the sarcoplasmic reticulum (SR); but in the nuclear envelope (NE) of cardiomyocytes (CMs), the PLB to SERCA2a molar ratio is higher, which highlights our poor understanding of how SR proteins distribute to their functional subcompartments. By tracking newly made PLB and SERCA2a in CMs, we will elucidate underlying cellular pathways responsible for their unique intracellular distributions.
Methods And Results: Highly specific monoclonal antibodies were used to compare the subcellular distributions of SERCA2a, PLB, and junctin (JCN) in dog heart tissue.