Antimicrobial Resistance of Human Species Infections in Saskatchewan, Canada (1999-2006): A Historical Provincial Collection of All Reported Cases.

To describe a historical baseline of antimicrobial resistance (AMR) profiles for human clinical species isolates obtained by laboratory surveillance in the province of Saskatchewan from 1999 to 2006; to determine if there were differences in resistance between and ; and to determine if there were changes in the annual resistance levels in the two species. One thousand three hundred seventy-eight isolates were subjected to antimicrobial susceptibility testing using the E-test method. Annual resistance levels in and were compared using logistic regression models.

Laboratory-Acquired Infection with Salmonella enterica Serovar Typhimurium Exposed by Whole-Genome Sequencing.

Despite advances in laboratory design, professional training, and workplace biosafety guidelines, laboratory-acquired infections continue to occur. Effective tools are required to investigate cases and prevent future illness. Here, we demonstrate the value of whole-genome sequencing as a tool for the identification and source attribution of laboratory-acquired salmonellosis.