is an emerging tick-borne pathogen in the Northern Hemisphere and is the causative agent of disease (BMD). is vectored by the same hard-bodied ticks as Lyme disease , yet phylogenetically groups with relapsing fever and thus, has been uniquely labeled a hard tick-borne relapsing fever . Burgeoning research has uncovered new aspects of in human patients, nature, and the lab.
View Article and Find Full Text PDFLeprosy and tuberculosis are infectious diseases that are caused by bacteria, and both share primary risk factors. Mediators of these diseases are regulated by a heterogeneous immature population of myeloid cells called myeloid-derived suppressor cells (MDSCs) that exhibit immunosuppressive activity against innate and adaptive immunity. During pathological conditions, endoplasmic reticulum (ER) stress occurs in MDSCs, and high levels of ER stress affect MDSC-linked immunosuppressive activity.
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