Understanding functional brain reorganization for naturalistic piano playing in novice pianists.

Learning to play the piano is a unique complex task, integrating multiple sensory modalities and higher order cognitive functions. Longitudinal neuroimaging studies on adult novice musicians show training-related functional changes in music perception tasks. The reorganization of brain activity while actually playing an instrument was studied only on a very short time frame of a single fMRI session, and longer interventions have not yet been performed.

Interoception and the musical brain: Evidence from cross-sectional and longitudinal behavioral and resting-state fMRI study.

Musical training has been linked to enhanced interoceptive abilities and increased resting-state (RS) functional connectivity (FC) within the interoceptive brain network. We aimed to replicate and extend these findings with a unique cross-sectional and longitudinal study design. Professional musicians and matched individuals with no prior musical experience (training group) were recruited.

Unlocking the musical brain: A proof-of-concept study on playing the piano in MRI scanner with naturalistic stimuli.

Music is a universal human phenomenon, and can be studied for itself or as a window into the understanding of the brain. Few neuroimaging studies investigate actual playing in the MRI scanner, likely because of the lack of available experimental hardware and analysis tools. Here, we offer an innovative paradigm that addresses this issue in neuromusicology using naturalistic, polyphonic musical stimuli, presents a commercially available MRI-compatible piano, and a flexible approach to quantify participant's performance.

Learning about threat from friends and strangers is equally effective: An fMRI study on observational fear conditioning.

Humans often benefit from social cues when learning about the world. For instance, learning about threats from others can save the individual from dangerous first-hand experiences. Familiarity is believed to increase the effectiveness of social learning, but it is not clear whether it plays a role in learning about threats.

Self-regulation and learning from failures: Probabilistic reversal learning task reveals lower flexibility persisting after punishment in procrastinators.

Procrastination is a self-regulation failure in which people irrationally delay intended actions which leads to lower performance, satisfaction from achievements, and quality of life. Trait procrastination is estimated to affect 15% to 20% of the total population, and previous studies have shown procrastination to be related to impulsivity, emotion dysregulation, and executive dysfunctions, making it a good nonclinical example of a self-regulation disorder. Our previous fMRI results revealed impaired error processing (lower error-related activity of the anterior cingulate cortex) and lack of ability to intensify executive-control during the punishment context (no increase in activity in prefrontal regions) in procrastinators.

The influence of light exposure and chronotype on working memory in humans.

Here we examine how exposure to blue (peaking at λ=470 nm), green (peaking at λ=505 nm) and red (peaking at λ=630 nm) light affects subsequent working memory performance measured with visual N-back tasks and associated functional brain responses in participants with extreme morning and extreme evening chronotype. We used within-subjects experimental manipulation on carefully selected samples and state of the art equipment for light exposure. The results show no differences between extreme morning-type and evening-type individuals in N-back task performance.

Male sexual orientation, gender nonconformity, and neural activity during mental rotations: an fMRI study.

The cross-sex shift hypothesis predicts that gay men should perform more like heterosexual women on important neurocognitive tasks on which men score higher than women, such as mental rotation. Studies also suggest sex differences exist in the neural correlates of mental rotation. However, no studies have taken sexual orientation into account or considered within-group variation attributable to recalled gender nonconformity (a developmental trait reliably associated with human nonheterosexuality).

Functional hierarchy for tactile processing in the visual cortex of sighted adults.

Perception via different sensory modalities was traditionally believed to be supported by largely separate brain systems. However, a growing number of studies demonstrate that the visual cortices of typical, sighted adults are involved in tactile and auditory perceptual processing. Here, we investigated the spatiotemporal dynamics of the visual cortex's involvement in a complex tactile task: Braille letter recognition.

Attenuated brain activity during error processing and punishment anticipation in procrastination - a monetary Go/No-go fMRI study.

Procrastination is a self-regulatory failure in which people voluntarily but irrationally delay important tasks. Trait procrastination is estimated to affect 15-20% of the total population and leads to a significant decrease in performance, satisfaction with achievements, and quality of life. Procrastination is related to impulsivity and reduced executive control, especially in the domain of inhibition.

The Set of Fear Inducing Pictures (SFIP): Development and validation in fearful and nonfearful individuals.

Emotionally charged pictorial materials are frequently used in phobia research, but no existing standardized picture database is dedicated to the study of different phobias. The present work describes the results of two independent studies through which we sought to develop and validate this type of database-a Set of Fear Inducing Pictures (SFIP). In Study 1, 270 fear-relevant and 130 neutral stimuli were rated for fear, arousal, and valence by four groups of participants; small-animal (N = 34), blood/injection (N = 26), social-fearful (N = 35), and nonfearful participants (N = 22).

Neural response patterns in spider, blood-injection-injury and social fearful individuals: new insights from a simultaneous EEG/ECG-fMRI study.

In the present simultaneous EEG/ECG-fMRI study we compared the temporal and spatial characteristics of the brain responses and the cardiac activity during fear picture processing between spider, blood-injection-injury (BII) and social fearful as well as healthy (non-fearful) volunteers. All participants were presented with two neutral and six fear-related blocks of pictures: two social, two spider and two blood/injection fear blocks. In a social fear block neutral images were occasionally interspersed with photographs of angry faces and social exposure scenes.