Panaroma of microglia in traumatic brain injury: a bibliometric analysis and visualization study during 2000-2023.

Background: Traumatic brain injury (TBI) is a critical global health concern characterized by elevated rates of both morbidity and mortality. The pathological and physiological changes after TBI are closely related to microglia. Microglia, the primary immune cells in the brain, are closely linked to the mechanisms and treatment of TBI.

Microscopic and neuroendoscopic treatment of a large ruptured supratentorial dermoid cyst with extensive dissemination: a case report and literature review.

Introduction And Importance: Intracranial dermoid cysts are rare, constituting 0.04% to 0.6% of all intracranial tumors.

Cathepsin C Promotes Tumorigenesis in Bladder Cancer by Activating the Wnt/β-catenin Signalling Pathway.

Background: Cathepsin C (CTSC) participates in the development of numerous cancers; however, its function in bladder cancer (BCa) remains largely unknown.

Methods: Bioinformatics prediction, quantitative reverse transcription polymerase chain reaction (RT-qPCR) assay, and Western blot assay were used to determine CTSC expression in BCa tissues, paracancer tissues, BCa cells, and normal uroepithelial cells (SV-HUC-1). Colony formation, cell counting kit-8 (CCK-8), and Transwell assays were utilised to ascertain the involvement of CTSC in BCa.

Structural and Functional Differences in Small Intestinal and Fecal Microbiota: 16S rRNA Gene Investigation in Rats.

To compare the differences in floral composition and functions between the two types of microbiota, ileal contents and feces were collected from Sprague Dawley (SD) rats fed in a conventional or specific-pathogen free (SPF) environment and rats fed a high-fat diet (HFD), and the V3-V4 region of the 16S ribosomal ribonucleic acid (rRNA) gene in these rats was then amplified and sequenced. Compared with feces, about 60% of the bacterial genera in the ileum were exclusive, with low abundance (operational taxonomic units (OTUs) < 1000). Of bacteria shared between the ileum and feces, a few genera were highly abundant (dominant), whereas most had low abundance (less dominant).

Diagnostic value of the combination of DAPK methylation in urinary sediment and B ultrasound for recurrent urinary bladder cancer.

Background: Urinary bladder cancer (UBC) is the most common malignancy affecting the urinary system. This study aimed to investigate the diagnostic value of combining DAPK methylation in urinary sediment and B ultrasound in the detection of recurrent UBC.

Methods: A total of 1021 cases with primary UBC who underwent electrocision of bladder tumor through urethra were included in this study and followed up.

SKA3 is a prognostic biomarker and associated with immune infiltration in bladder cancer.

Background: Spindle and kinetochore‑associated complex subunit 3 (SKA3) has recently been considered a key regulator of carcinogenesis. However, the connection between SKA3 and immune cell infiltration remains unknown.

Methods: The current study investigated the expression mode, prognostic effect, and functional role of SKA3 in different tumors, particularly bladder cancer using numerous databases, comprising TIMER, GEPIA, HPA, UALCAN, PrognoScan, and Kaplan-Meier Plotter.

The association between NQO1 Pro187Ser polymorphism and bladder cancer susceptibility: a meta-analysis of 15 studies.

Nad(p)h: quinone oxidoreductase 1 (NQO1), an obligate two-electron reductase, plays an important role in reducing reactive quinones to less reactive and less toxic hydroquinones. Genetic variations in NQO1 gene that impede its enzyme function may be considered as putative risk factor for cancer. Numerous studies have been performed to investigate the association between NQO1 Pro187Ser polymorphism and bladder cancer risk; nevertheless, the results remain controversial.

[Clinical application of the disposable circumcision suture device in male circumcision].

Objective: To investigate the safety and efficiency of the disposable circumcision suture device (DCSD) in the surgical treatment of phimosis and redundant prepuce.

Methods: We randomly assigned 249 outpatients with phimosis or redundant prepuce to be treated with DCSD (n = 129) and by conventional circumcision (CC, n = 120), respectively. Then we compared the safety and efficiency of the two strategies.

[Meniscus injury in osteoarthritis of knee joints: under arthroscopy].

Objective: To study the occurrence rate of meniscus injury in osteoarthritis (OA) of knee joint and inquire into the significance of meniscus injury in diagnosis and treatment of OA.

Methods: 125 knees of 120 cases with OA as the first diagnosis were observed when debridement was done under arthroscopy. The occurrence rate of meniscus injury and the relationship between the degree of OA and meniscus injury were analyzed.

[Effects of enriched oxygen on human free radical metabolism during exercise at 5 380 m plateau].

Objective: To study the effect of enriched oxygen on free radical metabolism at high altitude.

Method: SOD, GSH-Px and MDA were measured in 10 health young men after step in a room with or without oxygen enrichment at high altitude of 5 380 m.

Result: After exercise in the oxygen-enriched room, SOD and GSH-Px increased significantly while MDA decreased notably (P<0.