Fractionated Stereotactic Radiation Therapy Using Volumetric Modulated Arc Therapy in Patients with Solitary Brain Metastases.

Purpose: To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy.

Methods: Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were recruited in this study. All targets within the same course received different prescriptions according to size.

Coexpression modules constructed by weighted gene co-expression network analysis indicate ubiquitin-mediated proteolysis as a potential biomarker of uveal melanoma.

Uveal melanoma (UM) is a tumor that affects individuals throughout the world. Although gene expression analysis of UM has been performed previously, systemic co-expression analysis for this type of cancer remains lacking. Microarray data of UM samples was obtained from the Genome Expression Omnibus (dataset GSE44295).

Tc-LHRH in tumor receptor imaging.

Detection of gonadotropin-releasing hormone (GnRH) also known as luteinizing hormone-releasing hormone (LHRH) in the relevant tumor tissue and normal tissues and organs expression was investigated. To examine the method of direct radio labeling of LHRH by Tc with relatively high radiochemical purity and stability, screening the best labeling conditions, to establish a simple and reliable method of preparation of Tc-LHRH was undertaken. The detection of radioisotope-labeled LHRH distribution in mice, LHRH receptor imaging for the study and treatment of cancer basis were evaluated.

Regression Analysis of Non-iatrogenic Factors That Determine Adherence to Radiation Therapy.

The aim of this study is to explore non-medical factors that determine withdrawal from radiation therapy. Data from 2,643 patients who received radiotherapy in our Hospital from March 2010 to March 2012 were collected. Using gender, age, stage of the disease, Karnofsky score, aim of radiation therapy, therapy technique, vocation, medical insurance, and educational status as variables, 43 patients who terminated radiation therapy due to non-medical causes and 43 who completed the recommended course in the same period of time were, respectively, allocated to study and control groups.