Clinical efficacy of allograft bone combined with calcium phosphate bone powder in repairing bone defects of benign bone tumors: A retrospective controlled study.

Objective: To evaluate the clinical efficacy of repairing bone defects caused by benign bone tumors using allograft bone combined with calcium phosphate bone powder.

Methods: A retrospective analysis was conducted on 55 patients (aged 10-61 years, mean 35 ± 13.2) with benign bone tumors treated at our hospital from June 2020 to December 2022.

Liquid nitrogen quenching for efficient Bifunctional electrocatalysts in water Splitting: Achieving four key objectives in one step.

Herein, a novel liquid nitrogen quenching treatment is proposed to achieve multifaceted modulation involving morphological modulation, lattice tensile strain modulation, metal active centre coordination reconstruction and grain boundary construction within a series of intermetallic compounds modified on a carbon substrate (CoFe-550/C, CoNi-550/C and FeNi-550/C, where 550 refers to liquid nitrogen quenching temperature and C refers to the carbon substrate). Noteworthily, the optimising intermediate absorption/desorption process is achieved by multifaceted modulation. Consequently, CoFe-550/C, CoNi-550/C and FeNi-550/C demonstrate considerable overpotential for hydrogen evolution reaction (59.

Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.

Osteosarcoma (OS) is a prevalent primary malignant bone tumor which lacks effective therapeutic interventions. Ferroptosis is a new form of programmed cell death characterized by iron-dependent accumulation of lethal lipid oxidation, which provides a potential alternative intervene for the OS treatment. Shikonin is the major bioactive component extracted from the roots of lithospermum erythrorhizon which is also known as "Zicao" in traditional Chinese medicine, has been proved to have exhibits remarkable anti-tumor properties in several cancers.

How to determine the course of preoperative chemotherapy for spinal tuberculosis: A single-center clinical study.

This study aims to explore the clinical efficacy and feasibility of preoperative 1-week chemotherapy for patients with spinal tuberculosis (STB) undergoing complete lesion removal. Clinical data of 76 patients with STB who underwent complete focal debridement in our hospital were collected from June 2020 to September 2023. The patients were divided into 38 cases of preoperative 1-week chemotherapy group (Group A) according to the length of preoperative chemotherapy, and 38 cases of preoperative 2 to 4-week chemotherapy group (Group B).

Mono-/Bimetallic Doped and Heterostructure Engineering for Electrochemical Energy Applications.

Designing efficient materials is crucial to meeting specific requirements in various electrochemical energy applications. Mono-/bimetallic doped and heterostructure engineering have attracted considerable research interest due to their unique functionalities and potential for electrochemical energy conversion and storage. However, addressing material imperfections such as low conductivity and poor active sites requires a strategic approach to design.

Cobalt nanoparticles intercalation coupled with tellurium-doping MXene for efficient electrocatalytic water splitting.

Nowadays, the inherent re-stacking nature and weak d-p hybridization orbital interactions within MXene remains significant challenges in the field of electrocatalytic water splitting, leading to unsatisfactory electrocatalytic activity and cycling stability. Herein, this work aims to address these challenges and improve electrocatalytic performance by utilizing cobalt nanoparticles intercalation coupled with enhanced π-donation effect. Specifically, cobalt nanoparticles are integrated into VC MXene nanosheets to mitigate the re-stacking issue.

Nickel/Cobalt Molybdate Hollow Rods Induced by Structure and Defect Engineering as Exceptional Electrode Materials for Hybrid Supercapacitor.

Oxygen defects and hollow structures positively impact pseudocapacitive properties of diffusion/surface-controlled processes, a component of critical importance when building high-performance supercapacitors. Hence, we fabricated hollow nickel/cobalt molybdate rods with O-defects (D-H-NiMoO @CoMoO ) through a soft-template and partial reduction method, enhancing D-H-NiMoO @CoMoO 's electrochemical performance, yielding a specific capacitance of 1329 F g , and demonstrating excellent durability with 95.8 % capacity retention after 3000 cycles.

3D Hollow Flower-like CoWO Derived from ZIF-67 Grown on Ni-foam for High-Performance Asymmetrical Supercapacitors.

A three-dimensional (3D) hollow CoWO composite grown on Ni-foam (3D-H CoWO /NF) based on a flower-like metal-organic framework (MOF) is designed by utilizing a facile dipping and hydrothermal approach. The 3D-H CoWO /NF not only possesses large specific areas and rich active sites, but also accommodates volume expansion/contraction during charge/discharge processes. In addition, the unique structure facilitates fast electron/ion transport of 3D-H CoWO /NF.

A novel dual-tasking hollow cube NiFeO-NiCo-LDH@rGO hierarchical material for high preformance supercapacitor and glucose sensor.

Binary transition metal oxides as electroactive materials have continuously aroused grumous attention due to their high theoretical specific capacitance, high valtage window, and multiple oxidation states. However, the tiny specific surface area, poor conductivity and unsatisfactory cycle stability limit their practical application. Hence, a synthetic strategy is designed to fabricate a dual-tasking hollow cube nickel ferrite (NiFeO) - based composite (NiFeO-NiCo-LDH@rGO) with hierarchical structure.

Facile Dual-Ligand Modulation Tactic toward Nickel-Cobalt Sulfides/Phosphides/Selenides as Supercapacitor Electrodes with Long-Term Durability and Electrochemical Activity.

The use of high electrochemical active binary nickel-cobalt sulfides/phosphides/selenides (Ni-Co-X, X = S, P, Se) as electrochemical energy storage materials still has a space for improvement because they become electrochemically unstable during long-term use. Herein, a facile and cost-effective dual-ligand synergistic modulation tactic is described to substantially improve the durability of Ni-Co-X (X = S, P, Se) at the atomic level by partially substituting S, P, and Se ligands into the nickel-cobalt hydroxide precursor, respectively. Remarkably, the dual-ligand electrodes on Ni-foam achieve superior durability and high electrochemical activity when used as positive electrodes in supercapacitors.

An image-processing strategy to extract important information suitable for a low-size stimulus pattern in a retinal prosthesis.

Background: A retinal prosthesis is designed to help the blind to obtain some sight. It consists of an external part and an internal part. The external part is made up of a camera, an image processor and an RF transmitter.

SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.

Objectives: Aberrant activation of the Wnt/beta-catenin signaling pathway is common in human cancers, including cervical cancer. The secreted frizzled-related proteins (SFRPs) function as Wnt antagonists and play important implications in carcinogenesis. Recently, we have shown that SFRP1 and SFRP2 are frequently downregulated through promoter hypermethylation.