Comparison of Xpert HPV and Hybrid Capture 2 DNA Test™ for detection of high-risk HPV infection in cervical atypical squamous cells of undetermined significance.

This study compares Xpert HPV and Hybrid Capture 2 High-Risk HPV DNA Test™ (hc2) for the detection of high-risk HPV infection in cervical smears. Papanicolaou smears with atypical squamous cells of undetermined significance (ASC-US) constituted the study specimens. Of the 168 ASC-US samples, 134 (79.

Angiosarcoma at the site of nonfunctioning arteriovenous fistula in a kidney transplant recipient.

Angiosarcoma is a rare malignant neoplasm of the endothelial cells of blood vessels or lymphatics. We report a case of a 46-year-old male patient with a kidney transplant who developed epithelioid angiosarcoma at the site of a nonfunctioning arteriovenous fistula in the antecubital fossa 3 years after renal transplantation. The patient had skin, soft tissue, and bone metastasis on presentation.

Progressive multifocal leukoencephalopathy (PML) in a patient with lymphoma treated with rituximab: A case report and literature review.

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused by reactivation of a latent JC polyoma virus. The first cases of PML were described 50 years ago in patients with lymphoma. PML typically occurs in immunocompromised individuals, particularly those infected with HIV.

Pigmented Bowen's disease of the penis and scrotum in a patient with AIDS.

Patients with HIV have higher risk of developing squamous cell carcinoma of the skin given the increased risk of HPV infection, which alters cell proliferation and apoptosis [1]. Pigmented Bowen's disease is an uncommon form of squamous cell carcinoma in-situ characterized by pigmented lesions that can clinically mimic superficial spreading melanoma, pigmented basal cell carcinoma, melanocytic nevus, Bowenoid papulosis, and seborrheic keratosis.

Acute fibrinous and organizing pneumonia.

A 45-year-old man presented with malaise, arthralgia, and dyspnea. The chest CT scan showed bilateral patchy consolidation in the lower lobes. A lung biopsy revealed intra-alveolar fibrin "balls" deposits and focal features of organizing pneumonia, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP).

Acanthamoeba encephalitis in a patient with systemic lupus treated with rituximab.

Acanthamoeba species are free-living protozoa that can infect humans and animals. Acanthamoeba can cause serious central nervous system infections in immunocompromised hosts. Here we report a case of Acanthamoeba encephalitis in a patient with lupus nephritis, 1 month after completing a course of rituximab, an anti-CD20 chimeric antibody.

Acute kidney injury secondary to lymphomatous infiltration and the role of kidney biopsy.

We report a 47-year-old male patient who developed acute kidney injury requiring hemodialysis, associated with massive enlargement of both kidneys. A part from intra-abdominal lymphadenopathy, there was no other organ or lymph node involvement. A kidney biopsy established the diagnosis of non-Hodgkin's lymphoma.

Low grade fibromyxoid sarcoma: report of a case with fine needle aspiration cytology and histologic correlation.

Background: Low grade fibromyxoid sarcoma has been fully described histologically; however, the fine needle aspiration (FNA) cytologic findings are scantily defined, and the distinction from other benign and malignant soft tissue tumors can be difficult.

Case: We examined FNA cytologic material from a slowly growing, large chest wall mass in a 28-year-old woman. The surgical specimen was processed for routine histology and immunohistochemical studies.