Spectroscopic aspects of underwater digital holography of plankton.

Monitoring the parameters and behavior of plankton makes it possible to assess the state of the aquatic ecosystem and detect the beginning of an environmental disaster at an early stage. In this respect, the most informative method for the in situ plankton study is underwater digital holography. This method allows obtaining information on the size, shape, and location of plankton individuals, as well as performing their classification and biotesting according to their behavioral responses using a submersible holographic camera non-invasively, in real time, and in the automatic mode.

Deciphering the neural responses to a naturalistic persuasive message.

Effective health promotion may benefit from understanding how persuasion emerges. While earlier research has identified brain regions implicated in persuasion, these studies often relied on event-related analyses and frequently simplified persuasive communications. The present study investigates the neural basis of valuation change induced by a persuasive healthy eating call, employing naturalistic stimuli.

LPS-Induced Acute Lung Injury: Analysis of the Development and Suppression by the TNF-α-Targeting Aptamer.

Acute lung injury (ALI) is a specific form of lung inflammation characterized by diffuse alveolar damage, noncardiogenic pulmonary edema, as well as a pulmonary and systemic inflammation. The pathogenesis of ALI involves a cascade inflammatory response accompanied by an increase in the local and systemic levels of proinflammatory cytokines and chemokines. The development of molecular tools targeting key components of cytokine signaling appears to be a promising approach in ALI treatment.

Lithium tantalate photonic integrated circuits for volume manufacturing.

Electro-optical photonic integrated circuits (PICs) based on lithium niobate (LiNbO) have demonstrated the vast capabilities of materials with a high Pockels coefficient. They enable linear and high-speed modulators operating at complementary metal-oxide-semiconductor voltage levels to be used in applications including data-centre communications, high-performance computing and photonic accelerators for AI. However, industrial use of this technology is hindered by the high cost per wafer and the limited wafer size.

Monitoring Bioindication of Plankton through the Analysis of the Fourier Spectra of the Underwater Digital Holographic Sensor Data.

The study presents a bioindication complex and a technology of the experiment based on a submersible digital holographic camera with advanced monitoring capabilities for the study of plankton and its behavioral characteristics in situ. Additional mechanical and software options expand the capabilities of the digital holographic camera, thus making it possible to adapt the depth of the holographing scene to the parameters of the plankton habitat, perform automatic registration of the "zero" frame and automatic calibration, and carry out natural experiments with plankton photostimulation. The paper considers the results of a long-term digital holographic experiment on the biotesting of the water area in Arctic latitudes.

Ukrainian Plant Trait Database: UkrTrait v. 1.0.

Background: Considering the growing demand for plant trait data and taking into account the lack of trait data from Eastern Europe, especially from its steppic region, we launched a new Ukrainian Plant Trait Database (UkrTrait v. 1.0) aiming at collecting all the available plant trait data from Ukraine.

Aptasensors Based on Non-Enzymatic Peroxidase Mimics: Current Progress and Challenges.

Immunoassays based on antibodies as recognizing elements and enzymes as signal-generating modules are extensively used now in clinical lab diagnostics, food, and environmental analyses. However, the application of natural enzymes and antibodies has some drawbacks, such as relatively high manufacturing costs, thermal instability, and lot-to-lot variations that lower the reproducibility of results. Oligonucleotide aptamers are able to specifically bind their targets with high affinity and selectivity, so they represent a prospective alternative to protein antibodies for analyte recognition.

Neurochronometry of choice-induced preference changes: when do preferences actually change?

According to cognitive dissonance theory, a discrepancy between preferences and actions may lead to the revaluation of preferences, increasing preference for the chosen options and decreasing for the rejected options. This phenomenon is known as the spreading of alternatives (SoA), which results in a choice-induced preference change (CIPC). Previous neuroimaging studies have identified several brain regions that play a role in cognitive dissonance.

Effect of School-Based Educational Intervention on Promoting Healthy Dietary Habits in Danish Schoolchildren: The FOODcamp Case Study.

The present study aimed to evaluate the effect of the school-based educational intervention "FOODcamp" on dietary habits among 6th-7th graders (aged 11-13 years), focusing on the food groups: fruits and vegetables, fish, meat, discretionary food, and sugar-sweetened beverages. In this cluster-based quasi-experimental controlled intervention study, 16 intervention classes (322 children) and 16 control classes (267 children) from nine schools were recruited during the school year 2019-2020. The children were asked to record their food intake for four consecutive days (Wednesday to Saturday) before (baseline) and after (follow-up) attending FOODcamp, using a validated self-administered web-based dietary record.

The Interleukine-17 Cytokine Family: Role in Development and Progression of Spondyloarthritis, Current and Potential Therapeutic Inhibitors.

Spondyloarthritis (SpA) encompasses a group of chronic inflammatory rheumatic diseases with a predilection for the spinal and sacroiliac joints, which include axial spondyloarthritis, psoriatic arthritis, reactive arthritis, arthritis associated with chronic inflammatory bowel disease, and undifferentiated spondyloarthritis. The prevalence of SpA in the population varies from 0.5 to 2%, most commonly affecting young people.

Neural mechanisms of expert persuasion on willingness to pay for sugar.

Sugar consumption is associated with many negative health consequences. It is, therefore, important to understand what can effectively influence individuals to consume less sugar. We recently showed that a healthy eating call by a health expert can significantly decrease the willingness to pay (WTP) for sugar-containing food.

Features of phototropic response of zooplankton to paired photostimulation under adverse environmental conditions.

Our previous studies showed that the change in the plankton response to light could be an indicator of environmental pollution. This study experimentally reveals that the response of Daphnia magna Straus and Daphnia pulex plankton ensembles to photostimulation depends on the intensity of the attracting light. This makes it difficult to identify the occurrence and change of pollutant concentration.

Aptamers for Addressed Boron Delivery in BNCT: Effect of Boron Cluster Attachment Site on Functional Activity.

Among the great variety of anti-cancer therapeutic strategies, boron neutron capture therapy (BNCT) represents a unique approach that doubles the targeting accuracy due to the precise positioning of a neutron beam and the addressed delivery of boron compounds. We have recently demonstrated the principal possibility of using a cell-specific 2'-F-RNA aptamer for the targeted delivery of boron clusters for BNCT. In the present study, we evaluated the amount of boron-loaded aptamer inside the cell via two independent methods: quantitative real-time polymerase chain reaction and inductive coupled plasma-atomic emission spectrometry.

[Efficiency of benzydamine use in treatment of URTI (including COVID-19) in child patients].

Share with healthcare practitioners personal experience of using benzydamine spray (Oralsept) in pediatric practice; present a clinical case, which, according to the author, can help doctors optimize approaches to the treatment of patients with acute respiratory viral infections (including COVID-19), thereby improving the quality of life of pediatric patients.

In Situ Measurements of Plankton Biorhythms Using Submersible Holographic Camera.

The paper presents a diagnostic complex for plankton studies using the miniDHC (digital holographic camera). Its capabilities to study the rhythmic processes in plankton ecosystems were demonstrated using the natural testing in Lake Baikal in summer. The results of in situ measurements of plankton to detect the synchronization of collective biological rhythms with medium parameters are presented and interpreted.

Aptamer-Based Biosensors for the Colorimetric Detection of Blood Biomarkers: Paving the Way to Clinical Laboratory Testing.

Clinical diagnostics for human diseases rely largely on enzyme immunoassays for the detection of blood biomarkers. Nevertheless, antibody-based test systems have a number of shortcomings that have stimulated a search for alternative diagnostic assays. Oligonucleotide aptamers are now considered as promising molecular recognizing elements for biosensors (aptasensors) due to their high affinity and specificity of target binding.

Immunohistochemical Expression of VDR in Myocardium: Postmortem Evaluation of COVID-19 Patients.

Morphological data on heart damage and its mechanisms due to extremely severe course of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection are limited, as well as data on the correlation of damage and expression of vitamin D receptors (VDRs). In this study, we analyzed a series of myocardial samples obtained during postmortem autopsy of 48 critically ill patients with COVID-19 who died with SARS-CoV-2-associated pneumonia. The purpose of the study was to evaluate immunohistochemical VDR expression in the myocardium.

Phototropic response features for different systematic groups of mesoplankton under adverse environmental conditions.

Current trends in the application of bioindication methods are related to the use of submersible tools that perform real-time measurements directly in the studied aquatic environment. The methods based on the registration of changes in the behavioral responses of zooplankton, in particular , which make up the vast majority of the biomass in water areas, seem quite promising. However, the multispecies composition of natural planktonic biocenoses poses the need to consider the potential difference in the sensitivity of organisms to pollutants.

[THE STATE OF THE ORAL CAVITY LOCAL IMMUNITY DURING THE TREATMENT WITH METAL BRACKET-SYSTEM].

Objective - to study the effect of braces on the dentoalveolar system and the occurrence of changes in the body as a whole. The study involved 25 patients, 15 women and 10 men aged 20 to 45 years, with an anomaly of occlusion of the dentition in the transversal and sagittal plane, crowded position of the teeth of the upper and lower dentition. All patients were treated orthodontically on the MBT prescription bracket system made of high-quality steel grade 17-4.

Underwater Holographic Sensor for Plankton Studies In Situ including Accompanying Measurements.

The paper presents an underwater holographic sensor to study marine particles-a miniDHC digital holographic camera, which may be used as part of a hydrobiological probe for accompanying (background) measurements. The results of field measurements of plankton are given and interpreted, their verification is performed. Errors of measurements and classification of plankton particles are estimated.

[The modern methods of evaluation of implementing personalized programs of prevention of age-associated diseases].

The development of preventive programs targeting specific groups of consumers of medical social services having age-related health and lifestyle characteristics is one of the most prospective methods to improve quality of medical care of the elderly and senile patients. The previously developed by Russian and foreign scientists programs of personalized prevention of age-related diseases make it possible to organize target groups of patients seeking medical services in both state and private health care organizations to be screened for conditions of medical and social significance from the point of view of preventive medicine. This permits to achieve a real integration of various components of preventive care that improves health of elderly and senile patients in terms of morphofunctional indices of patient's physical status, quality of life, degree of independence, and, as a result, quality and scope of implementation of preventive programs for elderly population.

Visualization of volumetric defects and dynamic processes in crystals by digital IR-holography.

The observation and study of defects of single-crystal multicomponent optical material is necessary to determine the qualitative characteristics and optical properties of a material and to diagnose its manufacturing procedures. This paper utilizes the digital IR-holography to measure the geometrical parameters, shape, and location of defects as well as to characterize them. The paper illustrates the examples of physical, chemical, and optical inhomogeneities.

Early institutionalized care disrupts the development of emotion processing in prosody.

Millions of children worldwide are raised in institutionalized settings. Unfortunately, institutionalized rearing is often characterized by psychosocial deprivation, leading to difficulties in numerous social, emotional, physical, and cognitive skills. One such skill is the ability to recognize emotional facial expressions.

Aptamers for Proteins Associated with Rheumatic Diseases: Progress, Challenges, and Prospects of Diagnostic and Therapeutic Applications.

Nucleic acid aptamers capable of affine and specific binding to their molecular targets have now established themselves as a very promising alternative to monoclonal antibodies for diagnostic and therapeutic applications. Although the main focus in aptamers' research and development for biomedicine is made on cardiovascular, infectious, and malignant diseases, the use of aptamers as therapeutic or diagnostic tools in the context of rheumatic diseases is no less important. In this review, we consider the main features of aptamers that make them valuable molecular tools for rheumatologists, and summarize the studies on the selection and application of aptamers for protein biomarkers associated with rheumatic diseases.