Investigation of the Effect of Astaxanthin on Autophagy in Renal Ischemia-reperfusion Modeled Rats.

Objective: The aim of this study was to investigate the effect of various astaxanthin (ATX) doses on oxidative damage and autophagy in renal ischemia-reperfusion (I/R) injury-modeled rats.

Methods: The rats were divided into five groups: sham group (n=8), I/R (n=8), I/R + 5 mg/kg ATX (n=8), I/R + 10 mg/kg ATX (n=8), and I/R + 25 mg/kg ATX (n=8) groups. ATX was dissolved in 5 mg/kg, 10 mg/kg, and 25 mg/kg olive oil for 7 days and administered to the rats in the experimental group.

Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography.

Aim: To examine the morphometric properties of the vessels forming the Willis polygon (WP) in patients with type 2 diabetes mellitus (T2DM) and hypertension (HT) and compare them with healthy individuals.

Material And Methods: Cranial Tomography Angiography (CTA) of 168 individuals were analyzed retrospectively. The individuals included in the study were divided into four groups according to the diagnosis.

Comparison of 'primary repair' and 'placing a drain without repair' methods in duodenum perforations.

Background: Duodenal ulcer perforation is a serious condition. A number of methods have been defined and used in surgical treatment. In this study, it was aimed to compare the effectiveness of 'primary repair' and 'drain placement without repair' methods in duodenal perforations using an animal model.

Evaluation of the relationship between nasal septal deviation and development of facial asymmetry with anthropometric measurements depending on age.

Aim: It was aimed to determine the change of facial asymmetry resulting from nasal septal deviation (SD) depending on age, gender, degree of deviation and the affected area besides the effect of SD on somatotype and craniofacial morphology.

Materials And Methods: 171 volunteers (90 males, 81 females), 27 individuals aged 9-13, 44 individuals aged 14-18, 44 individuals aged 19-23 and 56 individuals in control group participated in the study conducted in otorhinolaryngology polyclinic.11 photometric, 16 anthropometric measurements were taken from the participants.

Investigation of clinical and pathological findings due to anatomical localisation in patients with colorectal cancer.

Aim: We classified anatomical localisation tumours of patients diagnosed with colorectal cancer and undergoing surgery as right and left colon and we aimed to determine how this funding affects the prognosis of the disease and survival times.

Methods: In our study, 521 patients who applied to the general surgery outpatient clinic of İnönü University Turgut Özal Medical Center 19.06.

Comparison of the effects of conventional physiotherapy and proprioception exercises on pain and ankle proprioception in patients with lumbar radiculopathy.

Background: Lumbar radiculopathy is characterized by a significant amount of backache causing loss of workforce and is a significant health problem frequently seen in the general population.

Objective: The purpose of this study was to compare the effects of conventional physiotherapy (CT) and proprioception exercises (PE) on ankle proprioception and lumbar pain between patients with lumbar radiculopathy and a healthy control group.

Methods: In this randomized clinical trial, 89 patients referred to the Physical Medicine and Rehabilitation outpatient clinic were selected through convenience sampling.

Analysis of the effects of hypothalamic-pituitary-adrenal axis activity in menstrual cycle on ankle proprioception, dynamic balance scores and visual-auditory reaction times in healthy young women.

Objectives: Menstrual cycle (MC) can affect not only the female reproductive system, but also functions such as neuromuscular performance. For this reason, the aim of this study is to investigate the effect of hypothalamic-pituitary-adrenal axis (HPA) activity in MC on proprioception, balance and reaction times.

Methods: For cortisol analysis, saliva samples were taken from the same women (n=43) in the four phases of MC.

The effect of stress-induced cortisol increase on the sense of ankle proprioception.

Objectives: The aim of this study is to analyze the effect of stress-induced cortisol increase on the sense of ankle proprioception.

Patients And Methods: Between April 2016 and May 2016, a total of 60 students (30 males, 30 females; mean age: 19.2±1.

Effect of increase in cortisol level due to stress in healthy young individuals on dynamic and static balance scores.

Objective: Stress is a condition caused by various factors and characterized by imbalance in body functioning, impair in nervous system, and tension. The purpose of this study was to examine the effects of cortisol level, which increases in healthy young individuals due to stress, on dynamic and static balance scores as well as to present the results caused by high levels of stress.

Methods: In this study, 107 healthy medicine faculty students in their second year (who will take the same committee exam) aged between 19 and 23 years were included.

The evaluation of the effect of vaginal delivery and aging on anal sphincter anatomy and function.

Objective: This study was conducted to evaluate the effect of vaginal delivery and aging on anal sphincter anatomy and function.

Method: Asymptomatic thirty women were included in this prospective study. Group 1 included 10 women (age range: 18-50) who had never been pregnant.

The effects of pre-obesity on quality of life, disease activity, and functional status in patients with ankylosing spondylitis.

Objective: This study was an investigation of effects of pre-obesity on clinical characteristics and quality of life in patients with ankylosing spondylitis (AS).

Methods: Total of 28 AS patients and 30 age- and sex-matched healthy controls were included in the study. Patients and controls with any systemic inflammatory disease and/or cognitive and mental problems were excluded.

The clinical effects of somatotype difference on isokinetic knee muscle strength and dynamic balance scores.

Objectives: The aim of this study was to present the somatotype features of young individuals without any symptoms and to identify whether isokinetic knee muscle strength and dynamic balance scores are affected by somatotype difference.

Patients And Methods: A total of 146 participants (88 males, 58 females; mean age 22.5±1.

Quantitative Evaluation of Normal Aqueductal Cerebrospinal Fluid Flow Using Phase-Contrast Cine MRI According to Age and Sex.

The aim of this study was cerebrospinal fluid (CSF) flow quantification in the cerebral aqueduct using phase-contrast cine magnetic resonance ımaging (PCC-MRI) according to both sexes and three different age groups to obtain normative data. Seventy two volunteers with no cerebral pathology were included in this study. Subjects were divided into three age groups: 20-34 years, 35-49 years, and 50-65 years including equal gender groups.

Detailed Anatomical Analysis of the Sphenoid Sinus and Sphenoid Sinus Ostium by Cone-Beam Computed Tomography.

The aim of this study is the evaluation of the anatomical structures of sphenoid sinus ostium used as a reference point for transsphenoidal surgery by cone beam computed tomography. The authors' study was performed using the cone-beam computed tomography images of 16 to 82-year old 200 (112 female, 88 male) patients (Newton 5G, Verona, Italy). Septum deviation of sphenoid sinus and the distance between 2 ostia were evaluated by coronal and axial sections, respectively.

An Analysis of Morphometric Qualities of Bulbus Oculi in Cataract Patients: A Comparative Biometric Study.

Cataract is considered to be the primary reason for curable blindness that is caused by progressive loss of lens transparency and affects millions of people around the world. This study aims to analyze the changes in morphometric qualities of bulbus oculi (BO) as well as its morphometric measurements such as anterior chamber depth (ACD), lens thickness (LT), vitreous length (VL), axial length (AL), etc. depending on age and gender in cataract patients through comparison with healthy eyes.

Medicinal plant extract (Ankaferd Blood Stopper) application in deep tissue injuries in rats: histopathological investigation of the effect on regional and systemic tissues.

Background: This study was planned to evaluate both the histopathological changes under light microscope as well as the systemic organ effects following application of Ankaferd Blood Stopper® (ABS) (a mixture of five plant extracts) in an animal model of deep tissue hemorrhage.

Methods: A total of 50 Wistar Albino rats were divided into five groups of 10 rats each. The rats underwent femoral vein puncture and were treated with ABS tampon, ABS spray, or Surgicel, and one group was left untreated.

Comparison of transforming growth factor β1 concentrations in the ovaries of rats stimulated by human menopausal gonadotropin or recombinant follicle-stimulating hormone.

Objective: To compare the effects of human menopausal gonadotropins (hMG) and recombinant follicle stimulating hormone (rFSH) on transforming growth factor (TGF) β1 concentration in the rat ovary.

Study Design: Twenty-one fertile Wistar-Albino rats were divided into 3 groups of 7. Groups 1, 2 and 3 were injected with saline, hMG or rFSH, respectively, over 5 days, after which they underwent ovariectomy.

Effect of atorvastatin and ezetimibe treatment on serum lipid profile and oxidative state in rats fed with a high-cholesterol diet.

Introduction: The effects of ezetimibe and atorvastatin on serum lipid profile and oxidant-antioxidant system were investigated in rats.

Methods: Seventy-two Sprague-Dawley rats were assigned to 6 groups. Group 1 was fed with standard rat chow.

Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve.

Objective: Crush injury to the sciatic nerve causes oxidative stress. Alfa Lipoic acid (a-LA) is a neuroprotective metabolic antioxidant. This study was designed to investigate the antioxidant effects of pretreatment with a-LA on the crush injury of rat sciatic nerve.

The protective effect of erythropoietin on the acute phase of corrosive esophageal burns in a rat model.

Introduction: An experimental study was conducted to investigate the effects of erythropoietin on the acute phase of esophageal burn damage induced by sodium hydroxide.

Materials And Methods: A standard esophageal alkaline burn was produced by the application of 10% sodium hydroxide to the distal esophagus in an in vivo rat model. Fifty-six female rats were allocated into three groups: Group BC (baseline control, n = 8) rats were uninjured and untreated, Group PC (positive control, n = 24) rats were injured but untreated and Group EPO (erythropoietin-treated, n = 24) rats were injured and given subcutaneous erythropoietin (1,000 IU/kg per day), 15 min, 24, and 48 h after administration of the NaOH solution.

C2 intralaminar screw placement: a quantitative anatomical and morphometric evaluation.

Aim: To investigate the feasibility of placing a screw in the C2 lamina and evaluate the reliability of the surface of the dorsal arch of C2 as a landmark for determining the optimal site of screw entry.

Material And Methods: 88 adult human C2 spines were used. Seven measurements were determined for screw entry points, trajectories, and lengths for placement of intralaminar screws.