Background: Functional C-159T polymorphism in the promoter region of the CD14 lipopolysaccharide receptor has been reported to be associated with the development of tuberculosis (TB).
Objective: To assess the association of CD14 C-159T polymorphism and serum soluble CD14 (sCD14) levels with pulmonary tuberculosis (TB) in an Iranian population living in a TB-endemic area.
Design: A case-control study was performed prospectively on 120 newly diagnosed pulmonary TB patients and 131 healthy subjects.