Comparison of 3 intranasal mists for anesthetizing maxillary teeth in adults: A randomized, double-masked, multicenter phase 3 clinical trial.

Background: This double-masked, parallel-design, clinical trial assessed whether a combination nasal spray (K305; 3% tetracaine hydrochloride and 0.05% oxymetazoline hydrochloride) compared with a tetracaine-only spray and a placebo spray would be safer and superior in producing local anesthesia sufficient to complete a direct restorative procedure in maxillary nonmolar teeth.

Methods: The authors randomized eligible patients to receive K305 spray (n = 44), tetracaine hydrochloride spray (n = 44), or a placebo solution (n = 22).

Building on the proceedings of the McGill conference: implant-retained overdentures in an area of South America.

Purpose: Since the McGill consensus conference, numerous reports have proposed the advantages of the 2-implant-retained overdenture over the conventional denture in the restorative management of the edentulous mandible. The purpose of this article was to demonstrate the use of the 2-implant-retained overdenture in the restorative management of patients with edentulous mandibles in an impoverished population.

Materials: To address the study's purpose, the investigators initiated a retrospective cohort study and enrolled a sample of subjects who had mandibular 2-implant overdenture treatment using the protocol described within.

Evaluation of varied repair protocols applied to aged composite resin.

Purpose: This paper aims to examine varied surface treatments combined with adhesive bonding to ascertain the highest bond strength of the composite resin repair.

Materials And Methods: A total of 100 specimens was made using an increment technique. The prepared specimens were aged for 20 days in 37 degrees +/- 20 degrees C water and then kept for 24 h at room temperature.