The Utility of Serum Alpha-fetoprotein for Monitoring for Relapse of Alpha-fetoprotein-Positive Hepatoblastoma.

Hepatoblastoma is the most common liver malignancy in children. Treatment typically involves surgery and cisplatin-based chemotherapy. After therapy completion, children undergo repetitive surveillance imaging to screen for relapse, which occurs in <12% of cases.

Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.

Background: Allogeneic hematopoietic cell transplantation (allo-HCT) remains a curative option for patients with high-risk myeloid malignancies.

Procedure: We present our 10-year experience (October 2012 to October 2021) of consecutive allo-HCT in patients with myeloid malignancies treated on the pediatric HCT service and conditioned with myeloablative targeted dose-busulfan (BU), fludarabine (FLU), and melphalan (MEL). Twenty-three children, adolescents, and young adult patients (CAYA) (median age 15.

[Abdominal emergency surgery in the geriatric patients. Our experience].

The ageing process of general population implies new socio-sanitary problems. Indications for surgical intervention have been modified and enhanced. As far as elective surgery is concerned, the results in elderly subjects do not seem alarming, whereas less satisfactory results have been registered in the patients who underwent an emergency surgical intervention, where nowadays morbidity and mortality still turn out to be high.

[Surgery for complicated colonic diverticulitis. Our experience].

During the last two decades were observed 422 symptomatic patients with various degree of diverticular disease of the colon. 51 patients underwent surgery: 29 for stenosis (24) or occlusion (5), 4 for fistulas, 18 for perforation. The operations (26 emergencies, 25 elective) included: 21 cases of one-stage resection and anastomosis without protective colostomy, 16 with colostomy, 8 Hartmann's procedures, 7 Mikulicz's operations, 1 suturing of the diverticulum with colostomy.

[Report on a case of schwannoma of the neck: clinical and therapeutic considerations].

We present a case of schwannoma of the neck in 49-year-old man, which was symptomatic for a long period: paraesthesia for one year, cervical mass for 2-3 months and dysphagia during the last 20 days. After ultrasonography and magnetic resonance the patient was operated on and complete excision of the mass was performed. The operation was performed via a cervical approach: the nerves and vascular and muscular structures were carefully isolated and then preserved.

[Treatment of acute biliary pancreatitis: our experience].

The results of endoscopic and surgical treatment in 21 patients affected by acute biliary pancreatitis are reported. All patients were managed according to the same protocol. Once the diagnosis was formulated (pain, serum amylase, ultrasonography, cholestasis and/or cholangitis) and the severity evaluated (Ranson's criteria, glucose and urea levels), the 21 patients underwent endoscopic retrograde cholangiopanctratography--within 24 hours in 8 patients (predicted severe disease) or within 72 hours in 13 patients (predicted mild disease).

[Report of a case of Gardner's syndrome: clinical and epidemiologic considerations and review of the literature].

Familial adenomatous polyposis is a hereditary clinical syndrome characterised by the presence of numerous adenomatous polyps of the colon and rectum and by lesions in other organs. The disease affects various different tissues and characteristically presents a variable biological and clinical behaviour. Colon polyps are precancerous lesions and the certainty of their malignant evolution within the 3rd-4th decades of life is now practically an established, extensively documented fact.

[Laparoscopic versus mini-cholecystectomy: analysis of hospital costs and social costs in a prospective randomized study].

The aim of the study was to calculate the hospital and social costs in relation to efficacy of clinical outcome, hospital stay and time off work in two groups of patients randomly treated with laparoscopic or mini-cholecystectomy. One hundred and eighty-one patients with simple, symptomatic gallstone disease were included in the study; of these, 9 cases were excluded because of conversion to conventional cholecystectomy. Eighty-six cases underwent laparoscopic cholecystectomy and 86 mini-cholecystectomy.

[Richter's hernia: a clinical case and the clinico-therapeutic considerations].

The authors report a case of Richter's hernia. They underline main clinical and therapeutic patterns, emphasizing the need of an early diagnosis and surgery. This is a hernia of abdominal wall with partial entrapment of bowel wall (antimesenteric site) through a small ring.

[Critical review of treatment outcome in 54 patients with synchronous liver metastasis of colorectal cancer].

Short- and long-term results of the treatment of 54 patients (12.5%) with synchronous hepatic metastases were critically reviewed by means of retrospective analysis of 431 colorectal cancer patients surgically treated over a period ranging from January 1980 to December 1989. Incidence and stage of hepatic metastases (Gennari Classification, 1984) are not significantly correlated to stage (T3), grade (G2-G3) and mucinous colorectal tumours; but they are significantly correlated to metastatic lymph nodes (p < 0.

[Jejunal diverticulosis: report of a case and review of the literature].

The jejunal diverticula are a rare pathology, they are verifiable with an incidence from 0.06 to 1.3% autoptical reports.

[Warthin's tumor of the parotid. The signs of a case].

The authors report a case of Warthin's tumor associated with cat scratch disease placed in 2 nodes. Both arose at the same time and evolved rapidly. Diagnosis was made by histology after their removal.

[A case of intestinal occlusion caused by malignant ileal lymphoma].

The Authors review a case of intestinal non-Hodgkin lymphoma, whose clinical feature was an intestinal obstruction caused by ileoileal intussusception. Some findings which make it unusual are compared with those mentioned in the international literature.

[The reliability of the grading assessment of the biopsy samples in malignant colorectal neoplasms].

The authors evaluate the results of preoperative bioptic grading compared with those obtained from postoperative specimens. Altogether, there was nonagreement in 45% of cases; therefore there is the risk of underestimating the biological aggressiveness of the disease. In fact, 68% of patients who were assessed as G1 in preoperative staging were found to have a higher degree of neoplastic dedifferentiation.

[Diagnostic peritoneal lavage in abdominal traumatology. Review of the literature].

This paper presents an exhaustive review of the literature on diagnostic peritoneal lavage (indications, contraindications, technique and results), since nowadays this constitutes the simplest and most reliable diagnostic procedure for internal and open abdominal trauma.

Pilonidal sinus with an anal canal fistula. Report of a case.

A rare case of a pilonidal cyst with the fistulous tract situated inside the anal canal is described. This is the sixth such case in the medical literature.