Spatiotemporal distribution of cyanobacteria in relation to water chemistry of Sutlej River, Punjab (India).

In this investigation, the spatiotemporal distribution of cyanobacteria and their relationships with variations in water chemistry (physico-chemical parameters and heavy metal) of Sutlej River, Punjab (India) has been analyzed by employing multivariate statistical methods. Sutlej River exhibits a rich array of cyanobacterial diversity, comprising 28 species across 15 genera, distributed among 11 families and spanning 5 orders within the class Cyanophyceae. In terms of relative abundance, Microcystis aeruginosa (17.

CTDN (Convolutional Temporal Based Deep- Neural Network): An Improvised Stacked Hybrid Computational Approach for Anticancer Drug Response Prediction.

The characterization of drug - metabolizing enzymes is a significant problem for customized therapy. It is important to choose the right drugs for cancer victims, and the ability to forecast how those drugs will react is usually based on the available information, genetic sequence, and structural properties. To the finest of our knowledge, this is the first study to evaluate optimization algorithms for selection of features and pharmacogenetics categorization using classification methods based on a successful evolutionary algorithm using datasets from the Cancer Cell Line Encyclopaedia (CCLE) and Genomics of Drug Sensitivity in Cancer (GDSC).

A systematic literature review for the prediction of anticancer drug response using various machine-learning and deep-learning techniques.

Computational methods have gained prominence in healthcare research. The accessibility of healthcare data has greatly incited academicians and researchers to develop executions that help in prognosis of cancer drug response. Among various computational methods, machine-learning (ML) and deep-learning (DL) methods provide the most consistent and effectual approaches to handle the serious aftermaths of the deadly disease and drug administered to the patients.

Evaluation of growth and carotenoid production by a green microalga Scenedesmus quadricauda PUMCC 4.1.40. under optimized culture conditions.

Microalgae are a potential source of a wide range of food and novel value-added products. The versatility of microalgae to produce different kind of pigments is gaining interest as a sustainable source of natural carotenoids. Currently, commercial production of carotenoids from selected microalgae requires special culture conditions which are difficult to maintain.

Assessment of water quality condition and spatiotemporal patterns in selected wetlands of Punjab, India.

Wetlands are one of the most productive aquatic ecosystems on earth, and their water quality is an indicative of their suitability for maintaining various ecosystem services. In this study, different statistical techniques and water quality index (WQI) were employed to access the status and spatiotemporal patterns in water quality of seven selected (two natural and five manmade) wetlands of Punjab. The results revealed that the status of water quality in the selected wetlands was between good and poor during studied seasons (summer, monsoon, and winter) of year 2019.

Synchrotron-based VUV excitation-induced ultrahigh quality cool white light luminescence from Sm-doped ZnO.

We report that the rare-earth (RE) ion, Sm-doped ZnO, acts as white light emitting vacuum ultraviolet (VUV) phosphors and possesses an ultrahigh color rendering index (CRI) and color quality scale (CQS). The VUV-excited emission spectra measured from the synchrotron source reveal the emergence of multi-color emission bands in the visible-IR region and substantially depend on the concentration of ions. A mechanism is proposed to elucidate the origin behind the high-energy bandgap excitation of the host charge carrier and subsequent energy transfer to the states leading to additional green-yellow-orange emission bands of (→(=5/2,7/2,9/2)).

Bimetallic Implanted Plasmonic Photoanodes for TiO Sensitized Third Generation Solar Cells.

An auspicious way to enhance the power conversion efficiency (PCE) of third generation sensitized solar cells is to improve the light harvesting ability of TiO sensitizer and inhibition of back recombination reactions. In the present work, we have simultaneously comprehended both the factors using stable bimetallic Au and Ag metal nanoparticles (Mnps) embedded in TiO with ion implantation technique at lower fluence range; and explored them in third generation dye sensitized solar cells (DSSCs). The best performing Au-Ag implanted DSSC (Fluence- 6 × 10 ions cm) revealed 87.

Returning genomic results in a Federally Qualified Health Center: the intersection of precision medicine and social determinants of health.

Purpose: This report describes the return of sequencing results to low-income Latino participants recruited through a Federally Qualified Health Center (FQHC). We describe challenges in returning research results secondary to social determinants of health and present lessons learned to guide future genomic medicine implementation studies in low-resource settings.

Methods: Five hundred Latino adults (76% women) consented to research sequencing for a predetermined panel of actionable genes.

Interaction of pretilachlor with PS-II activity of the cyanobacterium Desmonostoc muscorum PUPCCC 405.10.

Interaction of pretilachlor with photosystem (PS)-II of the cyanobacterium Desmonostoc muscorum PUPCCC 405.10 has been studied in this paper. Pretilachlor negatively affected growth, chlorophyll a (Chl a), photosynthesis, and carbon dissimilation in a dose-dependent manner.

Improving Access to Care Through the Establishment of a Local, Teledermatology Network.

Access to dermatologic care is a major issue in the United States, especially within the un- and underinsured populations; technology, including teledermatology, will pay a role in improving access to care. We performed a prospective study between November 2016 and September 2017. We leveraged a partnership between Mayo Clinic and Mountain Park Health Clinic, a community clinic that primarily serves un- and underinsured populations.

High production of carotenoids by the green microalga Asterarcys quadricellulare PUMCC 5.1.1 under optimized culture conditions.

Since carotenoids are important as natural colorants, antioxidants, neutraceutics and pharmaceutics, the aim of the present study was to find a new good source of these pigments. We hereby report a green microalga Asterarcys quadricellulare PUMCC 5.1.

Fabrication of plasmonic dye-sensitized solar cells using ion-implanted photoanodes.

Plasmonic dye-sensitized solar cells containing metal nanoparticles suffer from stability issues due to their miscibility with liquid iodine-based electrolytes. To resolve the stability issue, herein, an ion implantation technique was explored to implant metal nanoparticles inside TiO, which protected these nanoparticles with a thin coverage of TiO melt and maintained the localized surface plasmon resonance oscillations of the metal nanoparticles to efficiently enhance their light absorption and make them corrosion resistant. Herein, Au nanoparticles were implanted into the TiO matrix up to the penetration depth of 22 nm, and their influence on the structural and optical properties of TiO was studied.

Developing a Process for Returning Medically Actionable Genomic Variants to Latino Patients in a Federally Qualified Health Center.

Aim: To develop a process for returning medically actionable genomic variants to Latino patients receiving care in a Federally Qualified Health Center.

Methods: Prior to recruitment, researchers met with primary care providers to (1) orient clinicians to the project, (2) establish a process for returning actionable and nonactionable results to participants and providers through the electronic health record, and (3) develop a process for offering clinical decision support for follow-up education and care. A Community Advisory Board was engaged to provide input on recruitment strategies and materials for conveying results to participants.

Clinical Characteristics, Complications, and Treatment Practices in Patients With RHD: 6-Year Results From HP-RHD Registry.

Background: Despite the high prevalence of rheumatic heart disease (RHD) in developing countries such as India, data on characteristics, complications, and treatment practices are lacking. The HP-RHD (Himachal Pradesh Rheumatic Heart Disease) registry aimed at reporting these parameters in patients with RHD from a northern state of India.

Methods: A total of 2,005 consecutive patients of RHD were enrolled over a period of 6 years (2011 to 2016) in the present study.

Cyanobacterial lectins characteristics and their role as antiviral agents.

Lectins are ubiquitous proteins/glycoproteins of non-immune origin that bind reversibly to carbohydrates in non-covalent and highly specific manner. These lectin-glycan interactions could be exploited for establishment of novel therapeutics, targeting the adherence stage of viruses and thus helpful in eliminating wide spread viral infections. Here the review focuses on the haemagglutination activity, carbohydrate specificity and characteristics of cyanobacterial lectins.

Simultaneous occurrence of Hodgkin's disease and tubercular lymphadenitis in the same cervical lymph node: a rare presentation.

Concomitant presentation of tuberculosis (TB) and lymphoma is a rare entity. A primary malignancy such as Hodgkin's disease (HD) may cause suppression of the cell-mediated immunity, which predisposes to a concomitant TB infection. We report a case of an 18-year-old man, who presented with fever and was found to have pallor, generalised lymphadenopathy, hepatosplenomegaly, ascites and pedal oedema.