Tools which simulate the evolution of uni-parentally transmitted elements of the human genome.

Several simulators have been recently developed in the field of evolutionary genetics which make it possible to test empirical data under hypotheses of genetic variation generated by evolutionary causes. In the perspectives opened in the post-genomic era, they need to meet the growing demand for flexible and computationally efficient algorithms capable of managing genome-wide population datasets. Backward and forward-in-time strategies are available when attempting to better understand the complexity of the evolutionary scenarios actually followed by real populations.

Moors and Saracens in Europe: estimating the medieval North African male legacy in southern Europe.

To investigate the male genetic legacy of the Arab rule in southern Europe during medieval times, we focused on specific Northwest African haplogroups and identified evolutionary close STR-defined haplotypes in Iberia, Sicily and the Italian peninsula. Our results point to a higher recent Northwest African contribution in Iberia and Sicily in agreement with historical data. southern Italian regions known to have experienced long-term Arab presence also show an enrichment of Northwest African types.