Publications by authors named "Davide M Vespasiani"
Article Synopsis
- Modern humans have mixed genetically with archaic hominins, particularly Denisovans, contributing up to 5% of Papuans' genome from these ancient relatives.
- Researchers examined 56 Papuan genomes to understand the effects of Denisovan and Neanderthal genetic variants in various cell types and functional elements, finding that archaic alleles are enriched in areas related to gene regulation and immune functions.
- They identified thousands of Denisovan and Neanderthal variants that could influence gene activity, validating the functional impact of some variants through experiments, which suggests archaic DNA plays a significant role in shaping modern human genetics and phenotypic traits, especially in non-African populations.
