Publications by authors named "Davide Giacomin"
Article Synopsis
- The study examines the risk of colorectal cancer (CRC) after the removal of low-risk and high-risk adenomas in patients who tested positive for fecal immunochemical tests (FIT) and underwent colonoscopy in Italy from 2002 to 2017.
- Researchers tracked 87,248 colonoscopy cases and found that those with high-risk adenomas had a significant increase in CRC incidence compared to those with negative colonoscopies, while those with low-risk adenomas did not show increased risk.
- The presence of specific risk factors such as the location and morphology of the adenomas, particularly in high-risk cases, contributed to the higher incidences of CRC observed in the follow-up period.
Background: Colorectal cancer (CRC) screening programs based on fecal immunochemical tests (FITs) represent the standard of care for population-based interventions. Their benefit depends on the identification of neoplasia at colonoscopy after FIT positivity. Colonoscopy quality measured by adenoma detection rate (ADR) may affect screening program effectiveness.
View Article and Find Full Text PDFBackground And Aims: There are few prospective data about the use of surveillance colonoscopy and the risk of recurrent neoplasia in first degree relatives (FDRs) of colorectal cancer (CRC) patients. We examined the use and yield of surveillance colonoscopy in a population-based screening program (Trentino, Italy) METHODS: 1252 FDRs have been included in this study. We calculated compliance (percentage of FDRs who underwent surveillance colonoscopy among those eligible), appropriateness of colonoscopy (appropriate if performed within 6 months of the guidelines recommended interval) and diagnostic yield for neoplasia.
View Article and Find Full Text PDFBackground: A screening colonoscopy is recommended in first-degree relatives (FDRs) of colorectal cancer patients; few prospective, controlled studies have evaluated colorectal findings in a population-based screening program.
Objective: To evaluate the prevalence of colorectal neoplasia (adenomas and adenocarcinomas) in this increased-risk population, to compare it with that of average-risk individuals, and to identify features that might allow risk stratification for neoplasia among FDRs.
Design: Cross-sectional study.