Publications by authors named "Davide Brancato"
Article Synopsis
- The study investigates the clinical presentation and mortality risk of SARS-CoV-2 in older adults from Southern Italy, focusing on factors like therapy and clinical course.
- During a retrospective cohort study at Partinico COVID Hospital, 47 patients were followed for 87 days, with 40% mortality and significant impacts from conditions like diabetes and dementia.
- Key findings indicated that monitoring factors like diabetes, chronic kidney failure, and neutrophil/lymphocyte ratio can help predict patient outcomes early in treatment, enhancing care for older, frail individuals.
Introduction: This study aimed at evaluating the efficacy and safety of dapagliflozin in patients with type 2 diabetes (T2D) who also received metformin in clinical practice in Italy.
Methods: This was a retrospective observational study and it included data from patients who received dapagliflozin 10 mg once daily in conjunction with metformin for 12 months (DAPA + MET). In those with inadequate glycemic control, insulin or glimepiride was added after 30 days (DAPA + MET + other glucose-lowering drugs).
Background: Audit is a clinical instrument of government characterized by a whole process of evaluation inter pares to improve medical behaviors in the clinical practice. Different endocrinopathies are underestimated in the clinical and diagnostics practice but they can be a real problem in patients admitted in the departments of Internal Medicine. The adrenal incidentaloma is an accidental discovery with an incidence equal to 4% in radiologic studies but it's rarely considereted in the internal disorders.
View Article and Find Full Text PDFBackground: This study evaluated the predictors of effectiveness and durability of insulin pump therapy in children and adolescents who have initiated continuous subcutaneous insulin infusion (CSII) within 2 years after the diagnosis of type 1 diabetes mellitus (T1DM).
Subjects And Methods: The charts of individuals with T1DM using insulin pumps who were treated at our center were reviewed, including subjects with age at onset of <22 years, interval between onset and insulin pump commencement (interval onset-commencement) of <2 years, use of pumps of >1 year, and use of glucose sensors for <4 weeks/year. The primary end point was the mean glycosylated hemoglobin (HbA1c) value (MHbA1c) throughout the follow-up.
Objective: A great number of factors can interfere with levothyroxine (LT4) tablet absorption, leading to increased serum thyroid-stimulating hormone (TSH) levels and, accordingly, to increased LT4 requirements. LT4 oral solution (LT4-OS) is a novel formulation with a pharmacokinetics profile different from those of tablets. The aim of this study was to retrospectively evaluate whether serum TSH levels were decreased after switching adult hypothyroid patients from the tablet to LT-OS.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the effectiveness of continuous glucose monitoring (CGM) in predicting diabetes in children who have incident hyperglycemia but are negative for certain autoantibodies.
- Thirty-one children were followed for about 24 months, comparing metabolic markers between those who developed diabetes (17) and those who didn't (14).
- Results showed specific CGM and glucose tolerance test markers had strong predictive capabilities for diabetes, suggesting that CGM is a valuable tool for early prediction in this population.
Background: Neck lymph nodes may be involved in the pathogenesis of chronic autoimmune thyroiditis (CAT). This study was undertaken to identify which of the sonographic features of cervical lymph nodes are readily applicable to patients affected by CAT compared to healthy control subjects.
Methods: We recruited 106 patients (92 females and 14 males) with CAT and 70 control subjects (53 females and 17 males) without clinical, biochemical, and ultrasonographic evidence of thyroid and neck diseases.