Serum heavy metals and breast cancer risk: A case-control study nested in the Florence cohort of the EPIC (European Prospective Investigation into Cancer and nutrition) study.

Background: Chronic exposure to heavy metals is of concern for its potential carcinogenic effect. An association with increased breast cancer (BC) risk was hypothesized, but literature data are conflicting and the question remains unresolved. We aimed to investigate the association between heavy metals and BC risk in a case-control study nested within the Florence section of the EPIC (European Prospective Investigation into Cancer and nutrition) cohort.

[Tuberculosis in Prato (Tuscany Region, Central Italy) in the period 2007-2014].

Objectives: a description of the epidemiology of tuberculosis in the province of Prato (Tuscany Region, Central Italy) during the period 2007-2014 and verify the latency time between the onset of symptoms and the start of therapy.

Design: descriptive, observational study.

Setting And Participants: tuberculosis cases were identified for the period 2007-2014 through an analysis of the notification files available at the Hygiene and Public Health Service of the Local Health Unit of Prato and through the Information System on Infectious Diseases database.