Effect of centration and circularity of manual capsulorrhexis on cataract surgery refractive outcomes.

Purpose: To determine if postoperative refractive outcome in cataract surgery relates to centration or circularity of the capsulorrhexis.

Design: Prospective, observational study.

Participants: One hundred thirteen eyes from 108 patients undergoing routine phacoemulsification cataract surgery with manual continuous curvilinear capsulorrhexis.

A case of biopsy-negative temporal arteritis--diagnostic challenges.

A patient with systemic symptoms but no visual loss was investigated for suspected giant cell arteritis. Initial temporal artery biopsy was reported as negative; however, she returned with visual loss 2 months later, and the diagnosis of giant cell arteritis was confirmed with a subsequent biopsy. In hindsight, signs suggestive of the disease were present in the original biopsy, although the usual diagnostic features were absent.

Tonography demonstrates reduced facility of outflow of aqueous humor in myocilin mutation carriers.

Purpose: To demonstrate the effect in vivo of the myocilin gene mutation Thr377Met on outflow facility of aqueous humor, as measured by tonography.

Materials And Methods: Forty-two members of a pedigree known to carry the Thr377Met mutation were examined for glaucoma, evaluated with tonography, and screened for myocilin mutations. Tonography was used to calculate the coefficient of aqueous outflow facility (C), as well as the ratio of the resting intraocular pressure to C (P(0)/C).