Navigation of intracardiac catheters by echocardiography is challenging because of the fundamental limitations of B-mode ultrasonography. We describe a catheter fitted with a piezoelectric crystal, which vibrates and produces an instantaneous marker in color flow Doppler scans. The navigation learning curve was explored first in six pigs.
View Article and Find Full Text PDFCatheters are increasingly used therapeutically and investigatively. With complex usage comes a need for more accurate intracardiac localization than traditional guidance can provide. An injection catheter navigated by ultrasound was designed and then tested in an open-chest model of acute ischemia in eight pigs.
View Article and Find Full Text PDFAims: To describe a new approach to percutaneous mitral valve repair and an illustrative first-in-man experience, we introduce a suture mediated "double orifice", "edge-to-edge" procedure which can be an effective surgical therapy for mitral regurgitation (MR) in selected patient.
Methods And Results: We describe a novel percutaneous approach to double orifice mitral repair utilising an intra-cardiac suture based system. The procedure was performed in 15 patients in four international centres.
Background: The edge-to-edge (Alfieri) technique for mitral valve repair is a versatile method of treating mitral insufficiency. Because of its simplicity, it has been applied in minimally invasive surgery, and recently, in the design of endovascular closed-heart devices.
Aim: The purpose of this study was to evaluate the acute in-vivo safety and feasibility of a novel percutaneous mitral valve repair system based on Alfieri technique in an animal model.
J Am Soc Echocardiogr
February 2006
Background: High-quality live imaging assessment of cardiac valves and cardiac anatomy is crucial for the success of percutaneous catheter-based mitral valve (MV) repair techniques. We examined the use of intracardiac echocardiography (ICE) in providing online ICE images necessary for successful perctunaneous MV repair by Alfieri stitch technique-based percutaneous edge-to-edge device in a swine model.
Methods: ICE was performed in 20 healthy adult pigs (90 +/- 8 kg, mean +/- SEM).