Mood symptoms correlate with kynurenine pathway metabolites following sports-related concussion.

Objective: An imbalance of neuroactive kynurenine pathway metabolites has been proposed as one mechanism behind the neuropsychiatric sequelae of certain neurological disorders. We hypothesized that concussed football players would have elevated plasma levels of neurotoxic kynurenine metabolites and reduced levels of neuroprotective metabolites relative to healthy football players and that altered kynurenine levels would correlate with post-concussion mood symptoms.

Methods: Mood scales and plasma concentrations of kynurenine metabolites were assessed in concussed (N=18; 1.

Recovery of cerebral blood flow following sports-related concussion.

Importance: Animal models suggest that reduced cerebral blood flow (CBF) is one of the most enduring physiological deficits following concussion. Despite this, longitudinal studies documenting serial changes in regional CBF following human concussion have yet to be performed.

Objective: To longitudinally assess the recovery of CBF in a carefully selected sample of collegiate athletes and compare time course of CBF recovery with that of cognitive and behavioral symptoms.

The underreporting of self-reported symptoms following sports-related concussion.

Objectives: This cohort study was conducted to examine patterns of symptom reporting in concussed athletes in two different testing environments.

Design: A prospective cohort study was conducted with repeated measures.

Methods: Self-reported symptoms collected by team athletic trainers using the ImPACT Post-Concussion Scale (PCS) were compared to symptoms collected in a confidential setting using structured interviews for depression and anxiety.

Leg and calf press training modes and their impact on jump performance adaptations.

To examine the effects of resistance exercise (REX) mode on jump performance, subjects were assigned to one of three groups over a 6-week period with no cross-over. Subjects were assigned to leg and calf press REX on either a standard (n = 10) or ergometer (n = 9) device while a third group (n = 9) served as controls (CTRL). REX subjects worked out twice per week, which consisted of a three-set, 10-repetition paradigm for leg and calf press exercises.