Publications by authors named "David Simanjuntak"
Indonesia is a big country with multiethnic populations whose gastric cancer risks have not been elucidated. We performed a nationwide survey and obtained histological specimens from 1053 individuals in 19 cities across the country. We examined the gastric mucosa, the topography, the atrophic gastritis risk factors, and the gastric cancer risk scores.
View Article and Find Full Text PDFInformation regarding Helicobacter pylori antibiotic resistance in Indonesia was previously inadequate. We assessed antibiotic susceptibility for H. pylori in Indonesia, and determined the association between virulence genes or genetic mutations and antibiotic resistance.
View Article and Find Full Text PDFWe measured the accuracy of the urine test (RAPIRUN) for detection of Helicobacter pylori infection in Indonesia (Jakarta, Pontianak, and Jayapura) using histology confirmed by immunohistochemistry and/or culture as gold standards. We also used immunohistochemistry to identify CagA phenotype and analyzed H. pylori CagA diversity in Indonesia.
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- * Certain ethnic groups, particularly Papuan, Batak, and Buginese, demonstrated a higher risk of infection compared to Javanese and other groups, with various risk factors such as age, religion, and water source identified.
- * The study showcased that while Javanese had a low prevalence of H. pylori, the infection risk varied significantly across different ethnicities and suggested improved understanding of these factors can aid in better public health strategies in Indonesia.
Background: It remains unclear whether the low incidence of gastric cancer in Indonesia is due to low infection rates only or is also related to low Helicobacter pylori pathogenicity. We collected H. pylori strains from the five largest islands in Indonesia and evaluated genetic virulence factors.
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