'Earlier than Early' Detection of Breast Cancer in Israeli Mutation Carriers Applying AI-Based Analysis to Consecutive MRI Scans.

Female (=) pathogenic variants (PVs) carriers are at a substantially higher risk for developing breast cancer (BC) compared with the average risk population. Detection of BC at an early stage significantly improves prognosis. To facilitate early BC detection, a surveillance scheme is offered to PV carriers from age 25-30 years that includes annual MRI based breast imaging.