Publications by authors named "David Septian Sumanto Marpaung"

The norovirus (NoV), known for its high contagion rate, is the leading cause of acute gastroenteritis. The development of a NoV vaccine is hindered by significant antigenic variation, lack of suitable models, unknown vaccine protection duration, limited human challenge studies, complex performance patterns, and the absence of a reliable in vitro cultivation system, making prevention, early detection, and control the only effective measures to mitigate outbreaks. This review aims to discuss about several norovirus biosensor for point-of-care analysis.

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The escalating threat of emerging diseases, often stemming from contaminants and lethal pathogens, has precipitated a heightened demand for sophisticated diagnostic tools. Within this landscape, the functional nucleic acid (FNA) biosensor, harnessing the power of single-stranded DNA (ssDNA), has emerged as a preeminent choice for target analyte detection. However, the dependence on ssDNA has raised difficulties in realizing it in biological samples.

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Article Synopsis
  • Cargo molecule-encapsulated DNA capsules created with a solid sacrificial template are gaining popularity for uses like biosensors and drug delivery, but how template properties affect their assembly and release is not well-studied.
  • The research involved adding ethylene glycol (EG) during the synthesis of CaCO particles to vary their size and surface traits, examining how these characteristics influenced the DNA capsules' ATP-responsive release behavior.
  • Key findings showed that the surface roughness of the CaCO particles significantly impacted the DNA shell's compactness post-template removal, with results indicating that capsules made with high EG concentrations had low leakage and efficient cargo release.
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The excessive amount of global plastic produced over the past century, together with poor waste management, has raised concerns about environmental sustainability. Plastic recycling has become a practical approach for diminishing plastic waste and maintaining sustainability among plastic waste management methods. Chemical and mechanical recycling are the typical approaches to recycling plastic waste, with a simple process, low cost, environmentally friendly process, and potential profitability.

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