Publications by authors named "David Scott McVey"
Article Synopsis
- Bluetongue (BT) is a viral disease spread by midges, affecting deer and livestock, leading to major economic losses due to decreased animal production and trade restrictions.
- Researchers face challenges in studying this disease's transmission via live vectors, so they often use virus injections from baby hamster kidney (BHK) cells to induce infections in experimental models.
- A recent study found that using midge cell-derived BTV-17 resulted in more severe disease symptoms and higher mortality in mice compared to BHK cell-derived viruses, suggesting this method better mimics natural infections without the complications of working with live midges.
Evidence of Active Orbivirus Transmission in 2016 in Kansas and Nebraska.
Vector Borne Zoonotic Dis
June 2024
Retrospective serological and case diagnostic data of endemic bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) provide evidence of viral transmission among livestock and wildlife from 2016 in Kansas and Nebraska. Serological testing of mature cattle in nine distinct regional zones of Kansas revealed 76% to 100% had detectable antibodies to BTV and/or EHDV. Specimens tested in the Kansas Veterinary Diagnostic Laboratory (55 submissions) were 51% test positive for antibodies to BTV and/or EHDV.
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- Classical swine fever (CSF) is a contagious viral disease affecting pigs and wild boars, posing significant issues in the pig industry globally.
- Rapid and accurate diagnosis is crucial for controlling CSF, as its symptoms can easily resemble those of other viral diseases in pigs.
- Recent advancements in diagnostic methods, along with established tests outlined in the OIE Terrestrial Manual, are highlighted, showcasing the need for improved technologies in the detection of CSF.
Background: Animal hosts may vary in their attraction and acceptability as components of the host location process for assessing preference, and biting rates of vectors and risk of exposure to pathogens. However, these parameters remain poorly understood for mosquito vectors of the Rift Valley fever (RVF), an arboviral disease, and for a community of mosquitoes.
Methods: Using three known livestock amplifiers of RVF virus including sheep, goat and cattle as bait in enclosure traps, we investigated the host-feeding patterns for a community of mosquitoes in Naivasha, an endemic area of Rift Valley fever (RVF), in a longitudinal study for six months (June-November 2015).
Vaccines for emerging and re-emerging viral diseases of companion animals.
Vet Clin North Am Small Anim Pract
July 2008
It is likely that new viral diseases may continue to emerge in companion animals. It is more likely that genetic or antigenic virus variants or geographically translocated viruses may emerge or re-emerge in companion animals, however. This latter possibility represents the greater risk.
View Article and Find Full Text PDFThe use of potency control testing is a valuable tool for testing the actual relative strength of manufactured assembly lots of vaccine. Biological-based manufacturing methods are inherently variable and potency testing is a tool to ensure lot-to-lot consistency of commercial vaccines. A strong historical link to clinical efficacy has been established where correlation to efficacy and adequate test validation have been achieved.
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