Publications by authors named "David S Torres"
Objective: This study tested a newly developed flexible fiber for CO(2) laser surgery.
Background Data: The lack of a flexible delivery system with the current CO(2) laser has limited its surgical application. We conducted in vitro and in vivo studies by using the skin tissue model of animals to test a new laser fiber system.
Objectives/hypothesis: The objective was to investigate the functional and histological properties of surgical procedures using a new carbon dioxide (CO2) laser fiber.
Study Design: In vitro and in vivo animal models.
Methods: In vitro experiments using porcine true vocal cord and arytenoid cartilage were designed to study the histological effects of using a photonic band-gap fiber assembly for CO2 laser energy delivery.
Article Synopsis
- Live mycobacteria, specifically Mycobacterium bovis (BCG), engage pattern recognition receptors like TLR4 and TLR2, impacting immune responses in vitro and in vivo.
- In experiments with TLR4 mutant mice, macrophages showed reduced TNF levels during BCG infection, but both mutant and control mice managed to control the infection over time, despite the mutants facing increased inflammation and other complications.
- Findings suggest that while TLR4 signaling isn't crucial for the initial fight against BCG, it plays an important role in managing inflammation during the chronic phase of the infection.