Publications by authors named "David S Roffman"
A review of the literature was conducted for clinical trials evaluating the antiplatelet P2Y12 receptor antagonists, clopidogrel, prasugrel, and ticagrelor, as well as the guidelines for the management of acute coronary syndrome (ACS) or myocardial infarction. Clinical guidelines recommend that patients with ACS be treated with dual oral antiplatelet therapy of aspirin plus clopidogrel, prasugrel, or ticagrelor. The selection of an appropriate antiplatelet agent depends on the treatment approach and a patient's bleeding risk and clinical history.
View Article and Find Full Text PDFPurpose: Adverse events that can occur in patients with acute coronary syndrome (ACS) following percutaneous coronary intervention (PCI), and with the use of oral antiplatelet agents are discussed.
Summary: Disruption of the vascular endothelium routinely occurs during PCI and stent placement, resulting in vascular injury. This injury can increase the risk of intracoronary thrombosis and subsequent ACS after PCI.
University of Maryland School of Pharmacy was in a quandary: its comprehensive mission required meeting state workforce needs while increasing educational quality, expanding research, and responding to service needs, but state resources were declining, faculty members were stressed, construction of a long-needed new building was stalled, and pressure to increase doctor of pharmacy (PharmD) enrollment was growing. A sharp challenge from the Board of Regents mobilized the school to quickly launch a growth initiative to accelerate PharmD program expansion through a satellite campus. Within 4 months, a plan was approved that not only led to enrollment growth, but also to a significant expansion of the faculty and staff, increased operating and capital budgets, and ground breaking for an $83 million new building.
View Article and Find Full Text PDFObjective: To evaluate the impact of advanced pharmacy practice experiences (APPEs) on doctor of pharmacy (PharmD) students' readiness for self-directed learning.
Methods: The Self-Directed Learning Readiness Scale (SDLRS) was administered to students prior to and after completing their APPEs. SDLRS is a validated instrument that determines the relative degree to which students have the attitudes and motivation to engage in self-directed learning.
Objective: To address the value of Board of Pharmaceutical Specialties (BPS) certification, particularly as perceived by different stakeholders (pharmacists, employers, government, and academia), and to draw a parallel between specialization and certification in pharmacy and in medicine.
Data Sources: Electronic databases (Medline, International Pharmaceutical Abstracts, Sociological Abstracts), associations/health care organizations Web sites, outside reports, and clinical pharmacists involved in certification processes.
Study Selection: Studies and reports that addressed the value of specialty certification were selected by the authors.
Objective: To discuss the controversy associated with the optimal dosing of angiotensin-converting enzyme (ACE) inhibitors in the management of patients with systolic heart failure; specifically, to review data related to the use of high-dose ACE inhibitors related to both neurohormonal and clinical outcomes associated with doses similar to, lower than, and higher than those used in the large, randomized clinical trials.
Data Sources: Primary, review, and meta-analysis articles were identified by MEDLINE search (1987-September 2002) and through secondary sources.
Study Selection And Data Extraction: All of the articles identified from the data sources were evaluated, and all information deemed relevant was included in this discussion.