Publications by authors named "David S Reich"
NPJ Digit Med
September 2024
Article Synopsis
- Increased intracranial pressure (ICP) ≥15 mmHg can harm neurological health, but measuring it traditionally requires invasive methods; researchers developed a new AI-based biomarker (aICP) using non-invasive extracranial waveform data instead.
- The aICP was validated using an independent dataset and showed good performance metrics with an area under the receiver operating characteristic curve (AUROC) of 0.80 and an accuracy of 73.8%.
- Further analysis indicated that higher aICP predictions are linked to specific health conditions, such as brain tumors and intracerebral hemorrhages, suggesting its potential clinical relevance.
Article Synopsis
- Increased intracranial pressure (ICP) can lead to serious neurological problems, but requires invasive methods for monitoring, prompting the need for a non-invasive alternative.
- The study focused on creating and validating an AI model that detects increased ICP using non-invasive physiological data from patients, rather than requiring direct ICP measurements.
- Developed using data from an ICU database, the AI model demonstrated high accuracy and sensitivity in detecting elevated ICP, with promising results in external validation from a separate hospital dataset.
