Publications by authors named "David Preciado"
Article Synopsis
- Immature dentate granule cells (DGCs) in the hippocampus are thought to be important for brain function, but their specific roles and responses to experiences like exploring new environments are not well understood.
- Research found that despite having hyperexcitable properties, immature DGCs showed lower levels of immediate early gene (IEG) proteins when exposed to a novel environment compared to mature DGCs.
- Further analysis using single-nuclei RNA-Sequencing revealed that immature DGCs had reduced transcriptional changes during activation, indicating a different response mechanism to experiences compared to mature DGCs.
