Genomic analysis of isolated from surface water and animal sources in Chile reveals new T6SS effector protein candidates.

Type VI Secretion Systems (T6SS), widely distributed in Gram-negative bacteria, contribute to interbacterial competition and pathogenesis through the translocation of effector proteins to target cells. harbor 5 pathogenicity islands encoding T6SS (SPI-6, SPI-19, SPI-20, SPI-21 and SPI-22), in which a limited number of effector proteins have been identified. Previous analyses by our group focused on the identification of candidate T6SS effectors and cognate immunity proteins in genomes deposited in public databases.

Identification and distribution of new candidate T6SS effectors encoded in Pathogenicity Island 6.

The type VI secretion system (T6SS) is a contact-dependent contractile multiprotein apparatus widely distributed in Gram-negative bacteria. These systems can deliver different effector proteins into target bacterial and/or eukaryotic cells, contributing to the environmental fitness and virulence of many bacterial pathogens. harbors five different T6SSs encoded in different genomic islands.

Transfer of T6SS from Gallinarum to Typhimurium Lacking T6SS Complements its Colonization Defect in Mice.

genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SS) contributes to Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SS) of Gallinarum contributes to chicken colonization. Interestingly, the T6SS of Gallinarum complemented the defect in chicken colonization of a Typhimurium strain that lacks the T6SS, suggesting that both T6SSs are interchangeable.

Identification of Type VI Secretion Systems Effector Proteins That Contribute to Interbacterial Competition in Dublin.

The Type VI Secretion System (T6SS) is a multiprotein device that has emerged as an important fitness and virulence factor for many Gram-negative bacteria through the injection of effector proteins into prokaryotic or eukaryotic cells a contractile mechanism. While some effector proteins specifically target bacterial or eukaryotic cells, others can target both types of cells (trans-kingdom effectors). In , five T6SS gene clusters have been identified within pathogenicity islands SPI-6, SPI-19, SPI-20, SPI-21, and SPI-22, which are differentially distributed among serotypes.

Corrigendum: Transduction as a Potential Dissemination Mechanism of a Clonal -Carrying Plasmid Isolated From of Multiple Serotypes and Isolation Sources.

[This corrects the article DOI: 10.3389/fmicb.2019.

Transduction as a Potential Dissemination Mechanism of a Clonal -Carrying Plasmid Isolated From of Multiple Serotypes and Isolation Sources.

Antimicrobial resistance is an increasing problem worldwide, and spp. resistance to quinolone was classified by WHO in the high priority list. Recent studies in Europe and in the US reported the presence of small plasmids carrying quinolone resistance in isolated from poultry and poultry products.

Two Phages of the Genera Subjected to 12 Hour Challenge on Infantis Showed Distinct Genotypic and Phenotypic Changes.

Infantis is considered in recent years an emerging serovar, as it has been associated with several outbreaks and multidrug resistance phenotypes. Phages appear as a possible alternative strategy to control Infantis (I). The aims of this work were to characterize two phages of the genus, isolated using the same strain of I, and to expose them to interact in challenge assays to identify genetic and phenotypic changes generated from these interactions.

Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella.

Therapeutic attenuated strains of Salmonella Typhimurium target and eradicate tumors in mouse models. However, the mechanism of S. Typhimurium for tumor targeting is still poorly understood.

Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts.

The type VI secretion system (T6SS) is a virulence factor for many Gram-negative bacteria. Salmonella genus harbors five phylogenetically distinct T6SS loci encoded in Salmonella Pathogenicity Islands (SPIs) SPI-6, SPI-19, SPI-20, SPI-21 and SPI-22, which are differentially distributed among serotypes. The T6SSs encoded in SPI-6 and SPI-19 contribute to pathogenesis of serotypes Typhimurium and Gallinarum in mice and chickens, respectively.

The type VI secretion system encoded in SPI-6 plays a role in gastrointestinal colonization and systemic spread of Salmonella enterica serovar Typhimurium in the chicken.

The role of the Salmonella Pathogenicity Islands (SPIs) in pathogenesis of Salmonella enterica Typhimurium infection in the chicken is poorly studied, while many studies have been completed in murine models. The Type VI Secretion System (T6SS) is a recently described protein secretion system in Gram-negative bacteria. The genus Salmonella contains five phylogenetically distinct T6SS encoded in differentially distributed genomic islands.

The type VI secretion system encoded in Salmonella pathogenicity island 19 is required for Salmonella enterica serotype Gallinarum survival within infected macrophages.

Salmonella enterica serotype Gallinarum is the causative agent of fowl typhoid, a disease characterized by high morbidity and mortality that causes major economic losses in poultry production. We have reported that S. Gallinarum harbors a type VI secretion system (T6SS) encoded in Salmonella pathogenicity island 19 (SPI-19) that is required for efficient colonization of chicks.