Correction: Selective recognition of DNA defects by cyclometalated Ir(iii) complexes.

Correction for 'Selective recognition of DNA defects by cyclometalated Ir(iii) complexes' by David Paul Elisa Dayanidhi et al., Dalton Trans., 2019, 48, 13536-13540, DOI: .

Selective Recognition of Conformation-Specific Arylamine-DNA Adduct in Frameshift Model by [Ru(phen)(dppz)].

Arylamine modification of guanine base at the G position in the I sequence (-GGCGCC-) causes a frameshift mutation. Polymerase and F NMR studies have shown that the next flanking base at the 3' position to the G adduct modulates the mutational outcome because of its different conformations. Here, we have studied the interaction of the 16-mer I sequence (5'-CTCTCGGCCXATCAC-3') (G = -acetyl-2-aminofluorene (AAF)-dG and X is either C or T) with [Ru(phen)(dppz)] (phen = 1,10-phenanthroline and dppz = dipyrido[3,2-:2',3'-]phenazine).

Selective recognition of DNA defects by cyclometalated Ir(iii) complexes.

Selective detection of DNA defects is an attractive approach for early detection of various tumors and diseases. Ru(ii), Rh(iii) and hybrid complexes have been reported in this regard. Here, we present three heteroleptic cyclometalated Ir(iii) complexes [Ir(phpy)2(imiphen)]+(Ir-1), [Ir(phpy)2(furphen)]+(Ir-2) and [Ir(phpy)2(faqphen)]+(Ir-3) where imiphen: 2-(1H-imidazol-2-yl)-1H-imidazo[4,5-f][1,10]phenanthroline; furphen: 2-(furan-2-yl)-1H-imidazo[4,5-f][1,10]phenanthroline and faqphen: 2-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)anthracene-9,10-dione have been synthesized and characterized by analytical techniques.